Evidence map›Paper›PMID 36042156›Full record

ArticleChild psychiatry and human development2024

Characteristics of the Symptoms of the Proposed ND-PAE Disorder in First Grade Children in a Community Sample.

Julie A Kable, Claire D Coles, Jennifer E Holton, Wendy O Kalberg, Philip A May, Christina D Chambers, Gretchen Bandoli

Open access · greenAbstract read
In one paragraph

Article in Child psychiatry and human development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Julie A KableDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA. jkabl01@emory.edu.ORCID 0000-0001-5008-0887
Claire D ColesDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Jennifer E HoltonDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Wendy O KalbergCenter on Alcoholism, Substance Abuse and Addictions, University of New Mexico, Albuquerque, NM, USA.
Philip A MayCenter on Alcoholism, Substance Abuse and Addictions, University of New Mexico, Albuquerque, NM, USA.
Christina D ChambersSchool of Medicine, University of California, San Diego, La Jolla, USA.
Gretchen BandoliSchool of Medicine, University of California, San Diego, La Jolla, USA.
Emory University · USUniversity of California San Diego · USUniversity of New Mexico · USUniversity of North Carolina at Chapel Hill · US

Funding

Whole Body Effects of PAE Across the Life Span: Early Markers of & Clinical Interventions for Children and Adolescents in UkraineU01AA014835 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHRISTINA CHAMBERS · 2003 to 2026
$12.1M
Collaboration to Establish the Prevalence of FASD in San Diego, CAU01AA019879 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHAMBERS, CHRISTINA · 2010 to 2017
$9.2M
Prevalence and Traits of FASD in the US Population: Evidence from SchoolsU01AA019894 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAY, PHILIP ALAN · 2010 to 2017
$9.2M
Reassessing FASD: Novel Approaches for Evaluating Exposure, Diagnosis and Outcomes in Children Prenatally Exposed to AlcoholR01AA027785 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANDOLI, GRETCHEN E. · 2020 to 2022
$1.5M
Applying Machine Learning in the Prediction and Identification of Children Affected by Prenatal Alcohol ExposureK01AA027811 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANDOLI, GRETCHEN E. · 2019 to 2023
$865k
NIAAA NIH HHS K01 AA027811NIAAA NIH HHS R01 AA027785NIAAA NIH HHS R01AA027785NIAAA NIH HHS U01 AA014835NIAAA NIH HHS U01 AA019879NIAAA NIH HHS U01AA019879-01NIAAA NIH HHS U01 AA019894NIAAA NIH HHS UO1 AA019879NIAAA NIH HHS UO1 AA019894
6 · The paper itself

Abstract

The proposed symptoms for Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE) were evaluated in children who participated in the Collaboration on Fetal Alcohol Spectrum Disorders Prevalence study. Children "at-risk" for ND-PAE (n = 204) were contrasted to children with no prenatal alcohol exposure, alcohol-related dysmorphia or growth deficits (n = 908). Symptoms were defined based on neuropsychological testing using two diagnostic threshold levels (1.0 and 1.5 STD). Individuals at risk for ND-PAE had higher endorsement rates of the self-regulation and adaptive impairments at the 1.0 threshold and of the neurocognitive and self-regulation impairments at the 1.5 threshold. Endorsement of the disorder significantly differed at the 1.0 threshold. Receiver operating characteristic curve analysis indicated that having an IQ below 70 was not predictive of the diagnosis but modifications of the IQ criterion improved predictive validity. Discrimination validity was poor without documentation of PAE which continues to be a necessity for a diagnosis of ND-PAE.

Indexed as

Fetal Alcohol Spectrum DisordersPrenatal Exposure Delayed EffectsChildEthanolFemaleHumansNeuropsychological TestsPregnancyROC CurveEthanolChildrenFetal alcoholND-PAEPrenatal alcoholPsychiatric disorder

Identifiers

PMID36042156
PMCPMC10874642
OpenAlexW4293860009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.