Evidence map›Paper›PMID 36042030›Full record

SynthesisInternational journal of colorectal disease2022

Diverticulitis does not increase the long-term risk of developing colon cancer: a systematic review and meta-analysis.

Laura Quitzau Mortensen, Jens Buciek, Kristoffer Andresen, Jacob Rosenberg

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Laura Quitzau MortensenCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark. lauraquitzau@outlook.com.ORCID http://orcid.org/0000-0001-5909-0133
Jens BuciekCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.ORCID http://orcid.org/0000-0003-3549-7689
Kristoffer AndresenCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.ORCID http://orcid.org/0000-0002-9820-3580
Jacob RosenbergCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.ORCID http://orcid.org/0000-0002-0063-1086
Herlev Hospital · DKUniversity of Copenhagen · DK

Funding

Aage og Johanne Louis-Hansens Fond 20-2B-7108A.P. Møller Fonden 20-L-0200Knud og Edith Eriksens Mindefond 62786-2020
6 · The paper itself

Abstract

purposeThe aim of this review was to examine if diverticulitis increases the long-term risk (> 6 months) of developing colon cancer.

methodsA systematic search was conducted in PubMed, Embase, and Cochrane CENTRAL. Google Scholar was also searched. We included studies with human adults of 18 years of age and above. Studies that included only patients with diverticulitis as well as studies comparing groups with and without diverticulitis were included. The primary outcome was the incidence of colon cancer 6 months or more after an episode of diverticulitis.

resultsTwelve records were included with 38,621 patients with diverticulitis. The crude rate of colon cancer among the prospectively followed populations with diverticulitis was by meta-analysis found to be 0.6% (95% CI 0.5-0.6%). The limitations of this review include heterogeneous reporting of outcomes across studies, specifically regarding population and outcome as well as variations in the design and reporting of the studies.

conclusionWe found that the long-term risk of colon cancer after diverticulitis is not increased. The results of our review support current practice on follow-up after an episode of diverticulitis with short-term follow-up being the primary focus.

Indexed as

Colonic NeoplasmsDiverticulitisDiverticulitis, ColonicAdultHumansColon cancerDiverticulitisLong-term riskSystematic review

Identifiers

PMID36042030
OpenAlexW4293685919

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.