ReviewCold Spring Harbor perspectives in medicine2022
Evolutionary Approaches in Aging Research.
Review in Cold Spring Harbor perspectives in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Statistical Methods in Aging Research: Improving Current Practices and Embracing Emerging Approaches.Annual review of statistics and its application · 2026Article
- Sex differences in health burdens across the lifespan in wild chimpanzees (Evolution, medicine, and public health · 2025Article
- Geroscience and Its Promise.Cold Spring Harbor perspectives in medicine · 2024Review
- Natural Animal Populations as Model Systems for Understanding Early Life Adversity Effects on Aging.Integrative and comparative biology · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
While evolutionary explanations for aging have been widely acknowledged, the application of evolutionary principles to the practice of aging research has, until recently, been limited. Aging research has been dominated by studies of populations in evolutionarily novel industrialized environments and by use of short-lived animal models that are distantly related to humans. In this review, I address several emerging areas of "evolutionarily relevant" aging research, which provide a valuable complement to conventional biomedical research on aging. Nonhuman primates offer particular value as both translational and comparative models due to their long life spans, shared evolutionary history with humans, and social complexity. Additionally, because the human organism evolved in a radically different environment than that in which most humans live today, studying populations living in diverse ecologies has redefined our understanding of healthy aging by revealing the contribution of industrialized human environments to age-related pathologies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.