Evidence map›Paper›PMID 36041053›Full record

ArticleDiabetes care2022

Impact of a Novel Diabetes Prevention Intervention for Early Slow Weight Loss Responders Among Adults With Prediabetes: An Adaptive Trial.

Carla K Miller, Haikady N Nagaraja, Jennifer Cheavens, Kentaro Fujita, Sophie Lazarus

Abstract readAdaptive Clinical Trial
In one paragraph

Article in Diabetes care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carla K MillerSchool of Public Health, Indiana University, Bloomington, IN.ORCID 0000-0002-1002-7288
Haikady N NagarajaDivision of Biostatistics, College of Public Health, Ohio State University, Columbus, OH.
Jennifer CheavensDepartment of Psychology, Ohio State University, Columbus, OH.
Kentaro FujitaDepartment of Psychology, Ohio State University, Columbus, OH.
Sophie LazarusDepartment of Psychiatry and Behavioral Health, Ohio State University, Columbus, OH.

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9M
Impact of Augmented Care at the Worksite for Diabetes PreventionR01DK112930 · NIDDK · TRUSTEES OF INDIANA UNIVERSITY · PI MILLER, CARLA K · 2017 to 2021
$3.2M
NCATS NIH HHS UL1 TR002733NIDDK NIH HHS R01 DK112930
6 · The paper itself

Abstract

objectiveSome people are slower to respond during lifestyle interventions. An adaptive "rescue" intervention may improve outcomes among slow responders. The impact of a worksite rescue intervention for early slow responders was evaluated. RESEARCH DESIGN AND

methodsEmployees ≥21 years old with prediabetes were stratified to intervention using a 2.5% weight loss (%WL) threshold at week 5. Outcomes were assessed at baseline and at 4 months using mixed-effect and linear regression models.

resultsSignificant improvement occurred in mean %WL, glycemia, total cholesterol, and triglycerides in the standard compared with the adaptive (Group Lifestyle Balance Plus [GLB+]) intervention (all P≤ 0.01). However, GLB+ participants also experienced a significant reduction in %WL and glycemia (all P < 0.01). The %WL at week 5 significantly predicted %WL at 4 months (P < 0.0001). The between-group difference of 4-month %WL was not significant for someone achieving 2.5%WL at week 5.

conclusionsDiabetes prevention programs should consider weight loss success following 1 month of treatment and offer a rescue intervention to early slow weight loss responders.

Indexed as

Diabetes MellitusPrediabetic StateAdultCholesterolHumansTriglyceridesWeight LossYoung AdultCholesterolTriglycerides

Identifiers

PMID36041053
PMCPMC9643139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.