ArticlePloS one2022
The application of allostasis and allostatic load in animal species: A scoping review.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Stress, needs, and behaviour: understanding chronic stress in pet domestic dogs (Canis lupus familiaris) from the prism of needs.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Reindeer health and supplementary feeding practices - a survey among herders in Norway and Sweden.Acta veterinaria Scandinavica · 2026Article
- 'Teleonomes in Tatters': The Welfare Costs of Selecting Dogs for Extreme Phenotypes, and the Case for Change.Animals : an open access journal from MDPI · 2026Article
- Melatonin administration as a strategy to mitigate weaning stress in Lacaune lambs.Frontiers in veterinary science · 2026Article
- Stress, Well-Being, and Reproduction in Wildlife.Advances in experimental medicine and biology · 2026Review
- A Collaborative Multiple Stressor Approach for Identifying Spatial Heterogeneities in Wildlife Health and Conservation Priorities.Integrative and comparative biology · 2025Article
- Integrating allostasis and emerging technologies to study complex diseases.Communications biology · 2025Review
- The effects of different sample storage conditions on faecal corticosterone metabolite measurements in northern bobwhite (Conservation physiology · 2025Article
- Measuring polar bear health using allostatic load.Conservation physiology · 2025Article
- Putting the health in hidden Markov models: incorporating allostatic load indices into movement ecology analyses.Conservation physiology · 2025Article
- Adrenal response to competitive singing: glucocorticoid metabolites in maleConservation physiology · 2025Article
- Physical Measures of Welfare in Fin (Animals : an open access journal from MDPI · 2024Article
- Mindfulness-Based Interventions and the Hypothalamic-Pituitary-Adrenal Axis: A Systematic Review.Neurology international · 2024Review
- Allostasis as a consequence of high heat load in grain-fed feedlot cattle.Translational animal science · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Principles of allostasis and allostatic load have been widely applied in human research to assess the impacts of chronic stress on physiological dysregulation. Over the last few decades, researchers have also applied these concepts to non-human animals. However, there is a lack of uniformity in how the concept of allostasis is described and assessed in animals. The objectives of this review were to: 1) describe the extent to which the concepts of allostasis and allostatic load are applied theoretically to animals, with a focus on which taxa and species are represented; 2) identify when direct assessments of allostasis or allostatic load are made, which species and contexts are represented, what biomarkers are used, and if an allostatic load index was constructed; and 3) detect gaps in the literature and identify areas for future research. A search was conducted using CABI, PubMed, Agricola, and BIOSIS databases, in addition to a complementary hand-search of 14 peer-reviewed journals. Search results were screened, and articles that included non-human animals, as well as the terms "allostasis" or "allostatic" in the full text, were included. A total of 572 articles met the inclusion criteria (108 reviews and 464 peer-reviewed original research). Species were represented across all taxa. A subset of 63 publications made direct assessments of allostatic load. Glucocorticoids were the most commonly used biomarker, and were the only biomarker measured in 25 publications. Only six of 63 publications (9.5%) constructed an allostatic load index, which is the preferred methodology in human research. Although concepts of allostasis and allostatic load are being applied broadly across animal species, most publications use single biomarkers that are more likely indicative of short-term rather than chronic stress. Researchers are encouraged to adopt methodologies used in human research, including the construction of species-specific allostatic load indexes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.