Evidence map›Paper›PMID 36040721›Full record

ArticleClinical cardiology2022

The impact of COVID-19 on clinical outcomes among acute myocardial infarction patients undergoing early invasive treatment strategy.

Prerna Sharma, Kajal Shah, Johanna Loomba, Arti Patel, Indika Mallawaarachchi, Olivia Blazek, Sarah Ratcliffe, Khadijah Breathett, Amber E Johnson, Angela M Taylor and 7 more

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Prerna SharmaDivision of Cardiovascular Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.ORCID http://orcid.org/0000-0003-1118-1698
Kajal ShahDepartment of Internal Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
Johanna LoombaIntegrated Translational Health Research Institute (iTHRIV), University of Virginia, Charlottesville, Virginia, USA.
Arti PatelIntegrated Translational Health Research Institute (iTHRIV), University of Virginia, Charlottesville, Virginia, USA.
Indika MallawaarachchiDepartment of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.
Olivia BlazekDepartment of Internal Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
Sarah RatcliffeDepartment of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.
Khadijah BreathettDivision of Cardiology, University of Arizona Medical Center, Tucson, Arizona, USA.
Amber E JohnsonDivision of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Angela M TaylorDivision of Cardiovascular Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
Michael SalernoDivision of Cardiovascular Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
Michael RagostaDivision of Cardiovascular Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
Nishtha SodhiDivision of Cardiovascular Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
Daniel AddisonDivision of Cardiology, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Selma MohammedDivision of Cardiology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Kenneth C BilchickDivision of Cardiovascular Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
Sula MazimbaDivision of Cardiovascular Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.
University of Virginia Medical Center · USUniversity of Virginia · USBanner - University Medical Center Tucson · USCreighton University · USHartford Hospital · USThe Ohio State University Wexner Medical Center · USUniversity of Pittsburgh Medical Center · US

Funding

CD2H - The National COVID Cohort Collaborative (N3C) IDeA CTR CollaborationU24TR002306 · NCATS · UNIVERSITY OF COLORADO DENVER · PI CHUTE, CHRISTOPHER G, EICHMANN, DAVID A. · 2017 to 2021
$28.9M
The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve HealthUL1TR003015 · NCATS · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, JOHNSTON, KAREN C. · 2019 to 2023
$20.3M
Multiscale Models for Predicting Short and Long-term Outcome of Cardiac Resynchronization TherapyR01HL159945 · NHLBI · UNIVERSITY OF VIRGINIA · PI BILCHICK, KENNETH C, HOLMES, JEFFREY W · 2021 to 2024
$2.6M
NCATS NIH HHS NCATS U24 TR002306NCATS NIH HHS U24 TR002306NCATS NIH HHS UL1 TR003015NHLBI NIH HHS R01 HL159945
6 · The paper itself

Abstract

backgroundThe implications of coronavirus disease 2019 (COVID-19) infection on outcomes after invasive therapeutic strategies among patients presenting with acute myocardial infarction (AMI) are not well studied. HYPOTHESIS: To assess the outcomes of COVID-19 patients presenting with AMI undergoing an early invasive treatment strategy.

methodsThis study was a cross-sectional, retrospective analysis of the National COVID Cohort Collaborative database including all patients presenting with a recorded diagnosis of AMI (ST-elevation myocardial infarction (MI) and non-ST elevation MI). COVID-19 positive patients with AMI were stratified into one of four groups: (1a) patients who had a coronary angiogram with percutaneous coronary intervention (PCI) within 3 days of their AMI; (1b) PCI within 3 days of AMI with coronary artery bypass graft (CABG) within 30 days; (2a) coronary angiogram without PCI and without CABG within 30 days; and (2b) coronary angiogram with CABG within 30 days. The main outcomes were respiratory failure, cardiogenic shock, prolonged length of stay, rehospitalization, and death.

resultsThere were 10 506 COVID-19 positive patients with a diagnosis of AMI. COVID-19 positive patients with PCI had 8.2 times higher odds of respiratory failure than COVID-19 negative patients (p = .001). The odds of prolonged length of stay were 1.7 times higher in COVID-19 patients who underwent PCI (p = .024) and 1.9 times higher in patients who underwent coronary angiogram followed by CABG (p = .001).

conclusionThese data demonstrate that COVID-19 positive patients with AMI undergoing early invasive coronary angiography had worse outcomes than COVID-19 negative patients.

Indexed as

COVID-19Myocardial InfarctionPercutaneous Coronary InterventionRespiratory InsufficiencyCross-Sectional StudiesHumansRetrospective StudiesTreatment Outcomecardiac catheterizationCOVID-19pediatric clinical cardiologypercutaneous coronary intervention

Identifiers

PMID36040721
PMCPMC9538930
OpenAlexW4293584162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.