Evidence map›Paper›PMID 36040358›Full record

ArticleVeterinary medicine and science2022

High seroprevalence of Leishmania infantum infection in dogs and its associated risk factors in selected towns of Southwest and West Shewa zones of Oromia, Ethiopia.

Endrias Zewdu Gebremedhin, Weraka Weya, Chala Dima, Demeke Zewde, Vincenzo Di Marco Lo Presti, Maria Vitale

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Endrias Zewdu GebremedhinDepartment of Veterinary Sciences, School of Veterinary Medicine, Ambo University, Ambo, Ethiopia.ORCID 0000-0002-9432-6532
Weraka WeyaDepartment of Veterinary Sciences, School of Veterinary Medicine, Ambo University, Ambo, Ethiopia.
Chala DimaNational Animal Health Diagnostic and Investigation Center, Sebeta, Ethiopia.
Demeke ZewdeNational Animal Health Diagnostic and Investigation Center, Sebeta, Ethiopia.
Vincenzo Di Marco Lo PrestiDepartment of Veterinary Sciences, School of Veterinary Medicine, Ambo University, Ambo, Ethiopia.
Maria VitaleLaboratory of Genetics of Microorganisms, Istituto Zooprofilattico Sperimentale of Sicily, Palermo, Italy.
Ambo University · ETAmhara Regional Health Bureau · ETIstituto Zooprofilattico Sperimentale Della Sicilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeishmania infantum infection can result in serious vector-borne zoonotic disease such as visceral leishmaniasis. The objectives of the study were to estimate the seroprevalence and associated risk factors in Weliso, Ambo, and Ejaji towns in the Southwest and West Shewa zones, Oromia, Ethiopia.

methodsA cross-sectional study was conducted from October 2019 to September 2020. A total of 368 canines were sampled for the study using a basic random sampling procedure. An Indirect ELISA kit was used to test the presence of rK39 antigen eliciting specific antibodies in a serum sample. The association between L. infantum seropositivity and possible risk factors was assessed using Pearson's Chi-square and logistic regression tests.

resultsThe overall seroprevalence of L. infantum in dogs was found to be 84.24% (95% confidence interval [CI]: 80%-88%) with seroprevalences ranging from 76.11% (95% CI: 67%-84%) in Ambo to 79.82% (95% CI: 71%-87%) in Weliso, and higher seroprevalence, in Ejaji 93.84% (95% CI: 89%-97%). In a univariable logistic regression analysis, town (p = 0.001), season (p = 0.001), mixed living (indoor/outdoor) environment (p = 0.003), and kebele (p ≤ 0.05) were all found to be significantly linked with L. infantum seropositivity. In the multivariable analysis, wet season (p = 0.001) and mixed living environments (p = 0.025) were found to be independent predictors of L. infantum seropositivity.

conclusionsThis is the first comprehensive report of L. infantum infection in Ethiopian dogs. The very high seroprevalence suggests that dogs may play an important role in maintaining and spreading the infection to humans. Improvement of the living environment and health care facilities for dogs and humans as well health education for people awareness is suggested.

Indexed as

Dog DiseasesLeishmania infantumLeishmaniasisAnimalsCitiesCross-Sectional StudiesDogsEthiopiaHumansRisk FactorsSeroepidemiologic StudiesdogsEthiopiaIndirect ELISArisk factorsseroprevalencevisceral leishmaniasis

Identifiers

PMID36040358
PMCPMC9677361
OpenAlexW4293574604

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.