Evidence map›Paper›PMID 36040298›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2022

A Reversibly Porous Supramolecular Peptide Framework.

Dominic F Brightwell, Giada Truccolo, Kushal Samanta, Elliott J Fenn, Simon J Holder, Helena J Shepherd, Chris S Hawes, Aniello Palma

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Emergent properties of supramolecular peptide assemblies.Chemical communications (Cambridge, England) · 2026
    Review
  4. Discrete Actuation of Water-Responsive Crystalline Metal-Peptide Frameworks.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Article
  6. A Reversibly Porous Supramolecular Peptide Framework.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dominic F BrightwellSupramolecular Interfacial and Synthetic Chemistry Group, School of Physical Sciences, Ingram Building, University of Kent, CT2 7NH, Canterbury, UK.
Giada TruccoloSupramolecular Interfacial and Synthetic Chemistry Group, School of Physical Sciences, Ingram Building, University of Kent, CT2 7NH, Canterbury, UK.
Kushal SamantaSupramolecular Interfacial and Synthetic Chemistry Group, School of Physical Sciences, Ingram Building, University of Kent, CT2 7NH, Canterbury, UK.
Elliott J FennSupramolecular Interfacial and Synthetic Chemistry Group, School of Physical Sciences, Ingram Building, University of Kent, CT2 7NH, Canterbury, UK.
Simon J HolderSupramolecular Interfacial and Synthetic Chemistry Group, School of Physical Sciences, Ingram Building, University of Kent, CT2 7NH, Canterbury, UK.
Helena J ShepherdSupramolecular Interfacial and Synthetic Chemistry Group, School of Physical Sciences, Ingram Building, University of Kent, CT2 7NH, Canterbury, UK.
Chris S HawesSchool of Chemical and Physical Sciences, Lennard-Jones Building, Keele University, ST5 5BG, Staffordshire, UK.
Aniello PalmaSupramolecular Interfacial and Synthetic Chemistry Group, School of Physical Sciences, Ingram Building, University of Kent, CT2 7NH, Canterbury, UK.ORCID http://orcid.org/0000-0001-9626-4390
University of Kent · GBKeele University · GB

Funding

Engineering and Physical Sciences Research Council EP/T016140/1Royal Society of Chemistry E21-9299054940Royal Society of Chemistry R19-2762
6 · The paper itself

Abstract

The ability to use bio-inspired building blocks in the assembly of novel supramolecular frameworks is at the forefront of an exciting research field. Herein, we present the first polyproline helix to self-assemble into a reversibly porous, crystalline, supramolecular peptide framework (SPF). This framework is assembled from a short oligoproline, adopting the polyproline II conformation, driven by hydrogen-bonding and dispersion interactions. Thermal activation, guest-induced dynamic porosity and enantioselective guest inclusion have been demonstrated for this novel system. The principles of the self-assembly associated with this SPF will be used as a blueprint allowing for the further development of helical peptide linkers in the rational design of SPFs and metal-peptide frameworks.

Indexed as

PeptidesHydrogen BondingMolecular ConformationPorosityPeptidesenantioselectivityhelical structureshost-guest systemspeptidespolyprolinesupramolecular chemistry

Identifiers

PMID36040298
PMCPMC9828346
OpenAlexW4293567456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.