Evidence map›Paper›PMID 36040200›Full record

ArticleJournal of clinical microbiology2022

Pathogen Detection in Infective Endocarditis Using Targeted Metagenomics on Whole Blood and Plasma: a Prospective Pilot Study.

Laure Flurin, Matthew J Wolf, Cody R Fisher, Edison J Cano Cevallos, James J Vaillant, Bobbi S Pritt, Daniel C DeSimone, Robin Patel

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Clinical Features of 186 Cases ofInfection and drug resistance · 2026
    Article
  3. Review
  4. Genomic reconstruction ofMicrobial genomics · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Novel Diagnostic Methods for Infective Endocarditis.International journal of molecular sciences · 2024
    Review
  12. Article
  13. Updates in Culture-Negative Endocarditis.Pathogens (Basel, Switzerland) · 2023
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Laure FlurinDivision of Clinical Microbiology, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.ORCID 0000-0001-5687-1081
Matthew J WolfDivision of Clinical Microbiology, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.
Cody R FisherDivision of Clinical Microbiology, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.ORCID 0000-0002-7230-1078
Edison J Cano CevallosDivision of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.ORCID 0000-0002-0154-2544
James J VaillantDivision of Clinical Microbiology, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.
Bobbi S PrittDivision of Clinical Microbiology, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.ORCID 0000-0003-0261-1326
Daniel C DeSimoneDivision of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.
Robin PatelDivision of Clinical Microbiology, Mayo Clinicgrid.66875.3a, Rochester, Minnesota, USA.ORCID 0000-0001-6344-4141
Mayo Clinic · USMemorial Healthcare System · US

Funding

Molecular Detection of Biofilms on Hip and Knee ImplantsR01AR056647 · NIAMS · MAYO CLINIC ROCHESTER · PI PATEL, ROBIN · 2009 to 2020
$4.5M
HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) R01AR056647Mayo Clinic (The Mayo Clinic)NIAMS NIH HHS R01 AR056647
6 · The paper itself

Abstract

Initial microbiologic diagnosis of infective endocarditis (IE) relies on blood cultures and

Indexed as

EndocarditisEndocarditis, BacterialHumansMetagenomicsPilot ProjectsProspective StudiesRNA, Ribosomal, 16SRNA, Ribosomal, 16S16S ribosomal RNA gene16S rRNA PCRendocarditisnext generation sequencingtargeted metagenomics

Identifiers

PMID36040200
PMCPMC9491191
OpenAlexW4293567527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.