Evidence map›Paper›PMID 36039920›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2023

Sense of vitality is associated with cardiovascular events in type 2 diabetes independently of traditional risk factors and arterial stiffness.

Marta Vergara, Carl Johan Östgren, Fredrik H Nyström, Hanna Israelsson

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01049737 (Cardiovascular Risk Factors in Patients With Diabetes -a Prospective Study in Primary Care), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01049737 completednot on this map

Cardiovascular Risk Factors in Patients With Diabetes -a Prospective Study in Primary Care

TypeobservationalSponsorLinkoeping UniversityRan2005 to 2012Enrolled761ConditionsDiabetes Mellitus Type 2, Cardiovascular Diseases
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Functioning and disability consequences of comorbid posttraumatic stress disorder and diabetes in Vietnam era men and women veterans.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  3. Observational
  4. Vitality Revisited: The Evolving Concept of Flourishing and Its Relevance to Personal and Public Health.International journal of environmental research and public health · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marta VergaraDepartment of Health, Medicine and Caring Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0001-5428-4588
Carl Johan ÖstgrenDepartment of Health, Medicine and Caring Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0003-1617-3179
Fredrik H NyströmDepartment of Health, Medicine and Caring Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0002-1680-1000
Hanna IsraelssonDepartment of Health, Medicine and Caring Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0002-0125-9589
Linköping University · SE

Funding

FuturumGE HealthcareKing Gustaf V and Queen Victoria Freemason FoundationMedical Research Council in Southeast SwedenSwedish Research Council 12661The County Council of Östergötland and Linköping UniversityThe Swedish Heart-Lung Foundation
6 · The paper itself

Abstract

aimsThe aim of this study was to determine if single items in the quality of life questionnaire short form 36 (SF36) were associated with cardiovascular events in patients with type 2 diabetes mellitus (T2DM).

methodsIn 756 T2DM patients (260 women) from the CARDIPP study, nine questions from the domains vitality and well-being in SF36 were analysed. Patients, 55-66 years, were recruited in 2005-2008 and followed up until 31 December 2018 for the incidence of major adverse cardiovascular events (MACE), that is, myocardial infarction, stroke or cardiovascular death.

resultsMedian follow-up time: 11.6 years, during which 119 (16%) MACE occurred. The SF36 items: 'seldom full of pep' (HR 1.2, 95% CI: 1.1-1.4, p = 0.006), 'seldom a lot of energy' (HR 1.3, 95%CI: 1.1-1.5, p < 0.001), 'worn out' (HR 1.2, 95%CI: 1.0-1.4, p = 0.020) and 'seldom happy' (HR 1.2, 95%CI: 1.0-1.4, p = 0.012) were independent risk factors for MACE in separate models, as well as male sex, diabetes duration, HbA

conclusionsOne single question regarding energy levels from SF36 may be used as an independent risk factor for cardiovascular events in T2DM patients in primary care, for both men and women. This item may be included in future risk assessment for use in clinical practice for cardiovascular risk stratification of T2DM patients.

trial registrationThe study was registered in clinicaltrial.gov (NCT01049737) in 14 January 2010.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Myocardial InfarctionVascular StiffnessFemaleHumansMalePulse Wave AnalysisQuality of LifeRisk Factorscardiovascular diseasesdiabetes mellitusprimary health carequality of liferisk factorstype 2

Identifiers

PMID36039920
PMCPMC10947232
OpenAlexW4292423663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.