Evidence map›Paper›PMID 36039823›Full record

ArticleNeuropsychopharmacology reports2022

A preliminary study on predictors of treatment response to repetitive transcranial magnetic stimulation in patients with treatment-resistant depression in Japan.

Haruki Ikawa, Mamoru Tochigi, Yoshihiro Noda, Hiroshi Oba, Tatsuro Kaminaga, Keita Sakurai, Emi Ikebuchi, Naoki Hayashi, Hiroshi Kunugi

Open access · goldAbstract read
In one paragraph

Article in Neuropsychopharmacology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Haruki IkawaDepartment of Neuropsychiatry, Teikyo University School of Medicine, Graduate School of Medicine, Itabashi, Japan.ORCID 0000-0003-3829-0472
Mamoru TochigiDepartment of Neuropsychiatry, Teikyo University School of Medicine, Graduate School of Medicine, Itabashi, Japan.
Yoshihiro NodaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Hiroshi ObaDepartment of Radiology, Teikyo University School of Medicine, Graduate School of Medicine, Itabashi, Japan.
Tatsuro KaminagaDepartment of Radiology, Teikyo University School of Medicine, Graduate School of Medicine, Itabashi, Japan.
Keita SakuraiDepartment of Radiology, National Center for Geriatrics and Gerontology, Obu, Japan.
Emi IkebuchiDepartment of Neuropsychiatry, Teikyo University School of Medicine, Graduate School of Medicine, Itabashi, Japan.
Naoki HayashiDepartment of Neuropsychiatry, Teikyo University School of Medicine, Graduate School of Medicine, Itabashi, Japan.
Hiroshi KunugiDepartment of Neuropsychiatry, Teikyo University School of Medicine, Graduate School of Medicine, Itabashi, Japan.
Teikyo University · JPKeio University · JPNational Center for Geriatrics and Gerontology · JPTeikyo Heisei University · JPUniversity of Electro-Communications · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrain imaging studies have reported that the effect of repetitive transcranial magnetic stimulation (rTMS) is associated with the activities of the dorsolateral prefrontal cortex (DLPFC) and ventral medial prefrontal cortex (VMPFC). However, few studies have been conducted in Japanese patients.

aimWe aimed to identify brain regions associated with depressive symptom changes by measuring regional cerebral blood flow (rCBF) in the DLPFC and VMPFC before and after the high-frequency rTMS to the left DLPFC in Japanese patients with treatment-resistant depression.

methodFourteen patients participated in the rTMS study and were assessed with the 17-item Hamilton depression rating scale (HAM-D

resultsDepression severity significantly decreased after 2 week (HAM-D

conclusionWe obtained supportive evidence for the effectiveness of rTMS to the prefrontal cortex in treatment-resistant depression, which may be associated with reduced rCBF of the right DLPFC before initiation of rTMS.

Indexed as

Major Depressive DisorderTranscranial Magnetic StimulationDepressionHumansJapanPrefrontal Cortexarterial spin labelingdorsolateral prefrontal cortexrepetitive transcranial magnetic stimulationtreatment-resistant depressionventrolateral prefrontal cortex

Identifiers

PMID36039823
PMCPMC9773710
OpenAlexW4293552311

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.