Evidence map›Paper›PMID 36039687›Full record

ArticleHospital pediatrics2022

COVID-19 Vaccination Intentions for Children With Medical Complexity.

Kristina Devi Howell, Michelle M Kelly, Gregory P DeMuri, Joseph A McBride, Barbara Katz, M Bruce Edmonson, Daniel J Sklansky, Kristin A Shadman, Mary L Ehlenbach, Sabrina M Butteris and 3 more

Abstract read
In one paragraph

Article in Hospital pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kristina Devi HowellDepartments of Pediatrics.
Michelle M KellyDepartments of Pediatrics.
Gregory P DeMuriDepartments of Pediatrics.
Joseph A McBrideDepartments of Pediatrics.
Barbara KatzFamily Voices of Wisconsin, Madison, Wisconsin.
M Bruce EdmonsonDepartments of Pediatrics.
Daniel J SklanskyDepartments of Pediatrics.
Kristin A ShadmanDepartments of Pediatrics.
Mary L EhlenbachDepartments of Pediatrics.
Sabrina M ButterisDepartments of Pediatrics.
Gemma WarnerDepartments of Pediatrics.
Qianqian ZhaoBiostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Ryan J CollerDepartments of Pediatrics.

Funding

ReSET: Restarting Safe Education and Testing for Children with Medical ComplexityOT2HD107558 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI COLLER, RYAN J, DEMURI, GREGORY P · 2021 to 2022
$3.0M
NICHD NIH HHS OT2 HD107558
6 · The paper itself

Abstract

objectivesThe chronic conditions and functional limitations experienced by children with medical complexity (CMC) place them at disproportionate risk for COVID-19 transmission and poor outcomes. To promote robust vaccination uptake, specific constructs associated with vaccine hesitancy must be understood. Our objective was to describe demographic, clinical, and vaccine perception variables associated with CMC parents' intention to vaccinate their child against COVID-19.

methodsWe conducted a cross-sectional survey (June-August 2021) for primary caregivers of CMC between ages 5 to 17 at an academic medical center in the Midwest. Multivariable logistic regression examined associations between vaccination intent and selected covariates.

resultsAmong 1330 families, 65.8% indicated vaccination intent. In multivariable models, demographics had minimal associations with vaccination intent; however, parents of younger children (<12 years) had significantly lower adjusted odds of vaccination intent (adjusted odds ratio [95% confidence interval]: 0.26 [0.17-0.3]) compared to parents of older children (≥12 years). CMC with higher severity of illness, ie, those with ≥1 hospitalization in the previous year (versus none) or >1 complex chronic condition (vs 1), had higher adjusted odds of vaccination intent (1.82 [1.14-2.92] and 1.77 [1.16-2.71], respectively). Vaccine perceptions associated with vaccine intention included "My doctor told me to get my child a COVID-19 vaccine" (2.82 [1.74-4.55]); and "I'm concerned about my child's side effects from the vaccine" (0.18 [0.12-0.26]).

conclusionsOne-third of CMC families expressed vaccine hesitation; however, constructs strongly associated with vaccination intent are potentially modifiable. Pediatrician endorsement of COVID-19 vaccination and careful counseling on side effects might be promising strategies to encourage uptake.

Indexed as

COVID-19COVID-19 VaccinesAdolescentChildChild, PreschoolCross-Sectional StudiesHealth Knowledge, Attitudes, PracticeHumansIntentionParentsVaccinationCOVID-19 Vaccines

Identifiers

PMID36039687
PMCPMC10039457

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.