ArticleAesthetic surgery journal2023
Enhancing Patient Outcomes in Aesthetic Breast Implant Procedures Using Proven Antimicrobial Breast Pocket Irrigations: A 20-Year Follow-up.
Article in Aesthetic surgery journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Breast Implant Illness: Symptoms, Outcomes with Explantation and Potential Etiologies-A Systematic Review and Meta-analysis.Aesthetic plastic surgery · 2025Pooled it
- Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction.JAMA network open · 2023Trial
- Institutional Review Board Approval of Plastic Surgery Studies: Why It Matters.Annals of plastic surgery · 2026Article
- Commentary on The Keller Funnel, Handedness, and Reducing Complications after Breast Augmentation.Aesthetic plastic surgery · 2026Article
- Irrigation Solutions in Wound Care and Breast Surgery: Evidence-Based Applications, Regulatory Considerations, and Future Directions.Journal of clinical medicine · 2025Article
- Adipose-derived mesenchymal stem cells for the prevention of capsular contracture.Journal of molecular medicine (Berlin, Germany) · 2025Article
- A Rebuttal of a Meta-analysis Supporting Breast Implant Pocket Antimicrobial Irrigation.Annals of plastic surgery · 2025Article
- Concentration of Povidone-Iodine Pocket Irrigation in Implant-Based Breast Surgery: A Scoping Review.Aesthetic plastic surgery · 2025Article
- Does the Omission of Cefazolin in Irrigation Solution Affect Outcomes in Prepectoral Direct-to-Implant Breast Reconstruction?Aesthetic plastic surgery · 2025Article
- Alternative Hydration of the Acellular Dermal Matrix (ADM) to Reduce the Rate of Infection of Breast Reconstructions.Aesthetic plastic surgery · 2025Article
- Drivers and Barriers of Breast Augmentation Surgery: Multinational Insights.Aesthetic surgery journal. Open forum · 2025Article
- Diagnosis and Treatment of Perioperative Allergic Complications: A Practical Review.Plastic and reconstructive surgery. Global open · 2024Review
- Advances on Capsular Contracture-Prevention and Management Strategies: A Narrative Review of the Literature.Plastic and reconstructive surgery. Global open · 2023Article
- The Case Against Betadine Irrigation of Breast Implant Pockets.Aesthetic plastic surgery · 2023Article
- The Role of Microorganisms in the Development of Breast Implant-Associated Anaplastic Large Cell Lymphoma.Pathogens (Basel, Switzerland) · 2023Review
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCapsular contracture (CC) remains the most common complication of implant-based aesthetic and reconstructive breast surgery. With subclinical infection proven to be the primary etiology, antimicrobial breast pocket irrigation has been recommended as the key step to reduce CC but has not been universally adopted.
objectivesThe purpose of this study was to review the rates of CC observed when applying proven antimicrobial breast pocket irrigations.
methodsData from patients undergoing cosmetic breast augmentation were recorded prospectively from 1997 to 2017. The irrigation was performed with either a Betadine-containing (50% Betadine or "Betadine triple") or a non-Betadine triple antibiotic regimen. The database was assessed to determine the type of implant used, the incidence of CC, and possible contributing factors. The degree of CC was recorded according to the Baker classification.
resultsA 20-year prospective data collection yielded 2088 patients with 4176 implants; of these patients, 826 had textured implants and 1262 had smooth implants. The incidence of Grade III/IV CC was found to be 0.57% in all patients undergoing primary breast augmentation (1.21% in textured implants and 0.16% in smooth implants).
conclusionsThis study constitutes the largest and longest review of CC in a controlled, single-surgeon setting. The incidence of CC is low and reinforces the efficacy/utility of antimicrobial breast pocket irrigation. Both the Betadine and non-Betadine antibiotic regimens were found to be effective, with the Betadine regimen being preferred. Universal adoption of Betadine-containing antimicrobial breast pocket irrigation is recommended to reduce CC and other device-associated infections. LEVEL OF EVIDENCE: 4:
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.