Evidence map›Paper›PMID 36039592›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2022

CagA and VacA inhibit gastric mucosal epithelial cell autophagy and promote the progression of gastric precancerous lesions.

Jiaxiang Zhang, Wenba Wang, Shuguang Yan, Jingtao Li, Hailiang Wei, Weihan Zhao

Open access · greenAbstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 10 citations in OpenAlex.

  1. Internalization ofAnnals of medicine · 2026
    Review
  2. Advances inOncology letters · 2026
    Review
  3. Article
  4. Article
  5. Update on the pathogenesis and clinical management ofWorld journal of gastrointestinal pathophysiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Association ofFrontiers in medicine · 2025
    Review
  10. Article
  11. Effects of Infection with Different Types ofInternational journal of general medicine · 2024
    Article
  12. Programmed cell death inFrontiers in cellular and infection microbiology · 2024
    Review
  13. Reactive Oxygen Species andAntioxidants (Basel, Switzerland) · 2023
    Review
  14. High-Salt Diet ExacerbatesJournal of personalized medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jiaxiang ZhangBasic Medical College, Shaanxi University of Traditional Chinese Medicine, Xianyang Shaanxi 712046. 2072170949@qq.com.
Wenba WangBasic Medical College, Shaanxi University of Traditional Chinese Medicine, Xianyang Shaanxi 712046.
Shuguang YanBasic Medical College, Shaanxi University of Traditional Chinese Medicine, Xianyang Shaanxi 712046. ysg2002.student@sina.com.
Jingtao LiDepartment of Hepatology, Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang Shaanxi 712000.
Hailiang WeiDepartment of Hepatology, Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang Shaanxi 712000.
Weihan ZhaoDepartment of Gastroenterology, Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang Shaanxi 712000, China.
Affiliated Hospital of Shaanxi University of Chinese Medicine · CNShaanxi University of Chinese Medicine · CN

Funding

the National Natural Science Foundation of China 81804082
6 · The paper itself

Abstract

Cytotoxin-associated gene A (CagA) and vacuolating cytotoxin A (VacA) are the keys to the pathogenic role of

Indexed as

Helicobacter InfectionsHelicobacter pyloriPrecancerous ConditionsAntigens, BacterialAutophagyBacterial ProteinsCytotoxinsEpithelial CellsHumansAntigens, BacterialBacterial ProteinsCytotoxinsautophagygastric cancergastric precancerous lesionsHelicobacter pylorivirulence factor

Identifiers

PMID36039592
PMCPMC10930283
OpenAlexW4293677399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.