Evidence map›Paper›PMID 36039583›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2022

Lipid metabolism analysis for peripheral blood in patients with alcohol

Yuzhu Yan, Yan Yu, Junye Liu, Heping Zhao, Jihan Wang

Open access · greenAbstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. [Mechanisms of RNA-binding protein phase separation in steroid-associated necrosis of the femoral head].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
  2. Article
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  6. Clinical Characteristics, Current Treatment Options, Potential Mechanisms, Biomarkers, and Therapeutic Targets in Avascular Necrosis of Femoral Head.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuzhu YanDepartment of Clinical Laboratory, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054. 312858826@qq.com.
Yan YuDepartment of Clinical Laboratory, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054.
Junye LiuDepartment of Clinical Laboratory, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054.
Heping ZhaoDepartment of Clinical Laboratory, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054. redcrossjyk@163.com.
Jihan WangXi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, China. jihanwang@nwpu.edu.cn.
Xi'an Honghui Hospital · CNNorthwestern Polytechnical University · CN

Funding

the Natural Science Foundation of Shaanxi Province 2019JJ50929the Science and Technology Plan Projects of Xi'an 2019115013YX005SF038(10)
6 · The paper itself

Abstract

objectivesOsteonecrosis of the femoral head (ONFH), also known as vascular necrosis of the femoral head, is combined with lipid metabolism disorders in most patients. This study aims to explore the lipid metabolism profiles in different subtypes of ONFH.

methodsThe subjects were divided into an alcohol-induced osteonecrosis of the femoral head (AONFH) group, a steroid-induced osteonecrosis of the femoral head (SONFH) group, and a normal control (NC) group (

resultsIn this study, 1 358 lipid metabolites were detected in each plasma sample. Compared with the NC group, there were significant difference in the expression patterns of lipid metabolism profiles in the AONFH group and the SONFH group. A total of 62 and 64 differential lipid metabolites were screened in the AONFH and SONFH patients (FC>2,

conclusionsThis study analyzes the characteristics of the plasma lipid metabolism profile in the AONFH and SONFH patients, and which identifies the differential lipid metabolites related to disease diagnosis and evaluation. These results provide evidence for exploring lipid metabolism alterations and the mining of novel lipid biomarkers for the ONFH.

Indexed as

Femur HeadFemur Head NecrosisBiomarkersChromatography, LiquidEthanolHumansLipid MetabolismLipidsSerotoninSteroidsTandem Mass SpectrometryBiomarkersEthanolLipidsSerotoninSteroidsalcohol-induced osteonecrosis of the femoral headARCO stagebiomarkerlipidomicssteroid-induced osteonecrosis of the femoral head

Identifiers

PMID36039583
PMCPMC10930281
OpenAlexW4293778501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.