Observational studyEuropean journal of neurology2022
Long-term fatigue following aneurysmal subarachnoid haemorrhage and the impact on employment.
Observational study in European journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- A Randomised Controlled Trial of SFX-01 After Subarachnoid Haemorrhage - The SAS Study.Translational stroke research · 2025Trial
- Longitudinal trajectories of functional outcome following aneurysmal subarachnoid hemorrhage: a retrospective study.Critical care (London, England) · 2026Article
- Distinct Cytokine Responses in Central and Systemic Compartments after Subarachnoid Haemorrhage.Translational stroke research · 2025Article
- C-reactive protein and fatigue after subarachnoid haemorrhage.Brain, behavior, & immunity - health · 2025Article
- Health-related quality of life after spontaneous subarachnoid hemorrhage - a prospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Neurobehavioral Impairments Predict Specific Cerebral Damage in Rat Model of Subarachnoid Hemorrhage.Translational stroke research · 2024Article
- An assistive listening device improves hearing following aneurysmal subarachnoid haemorrhage.European journal of neurology · 2024Article
- Fatigue, Toll-Like Receptor 4, and Pro-Inflammatory Cytokines in Adults With Subarachnoid Hemorrhage: A 6-Month Longitudinal Study.Biological research for nursing · 2024Review
- Return to work after aneurysmal subarachnoid hemorrhage.Frontiers in neurology · 2024Article
- Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation.Stroke · 2023Review
- Neurobehavioral impairments predict specific cerebral damage in rat model of subarachnoid hemorrhage.Research square · 2023Article
- Long-term fatigue following aneurysmal subarachnoid haemorrhage and the impact on employment.European journal of neurology · 2022Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
background and purposeFatigue is common following aneurysmal subarachnoid haemorrhage (aSAH) but little is known about its frequency, prognosis and impact on employment. The aim of this study was to assess the frequency of fatigue, whether it changes over time and the relationship to employment in the long term.
methodsThis was a retrospective observational study of aSAH cases and matched controls from the UK Biobank. The presence of fatigue was compared between cases and controls using the chi-squared test. The change in frequency over time was assessed using Spearman's rank correlation coefficient. The effect of fatigue on employment was assessed using mediation analysis.
resultsFatigue is more common following aSAH compared to matched controls (aSAH 18.7%; controls 13.7%; χ
conclusionsFatigue is common following aSAH and persists in the long term. It gradually improves over time but has a major impact on aSAH survivors, significantly contributing to unemployment following haemorrhage. Further work is required to develop treatments and management strategies for fatigue with a view to improving this symptom and consequently employment following aSAH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.