Evidence map›Paper›PMID 36039504›Full record

ArticleClinical rehabilitation2023

Post-fracture rehabilitation pathways and association with mortality among adults with cerebral palsy.

Daniel G Whitney, Tao Xu, Dayna Ryan, Daniel Whibley, Michelle S Caird, Edward A Hurvitz, Heidi Haapala

Abstract read
In one paragraph

Article in Clinical rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel G WhitneyDepartment of Physical Medicine and Rehabilitation, 1259University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-2132-1527
Tao XuKidney Epidemiology and Cost Center, School of Public Health, 1259University of Michigan, Ann Arbor, MI, USA.
Dayna RyanDepartment of Physical Medicine and Rehabilitation, 1259University of Michigan, Ann Arbor, MI, USA.
Daniel WhibleyDepartment of Physical Medicine and Rehabilitation, 1259University of Michigan, Ann Arbor, MI, USA.
Michelle S CairdDepartment of Orthopaedic Surgery, 1259University of Michigan, Ann Arbor, MI, USA.
Edward A HurvitzDepartment of Physical Medicine and Rehabilitation, 1259University of Michigan, Ann Arbor, MI, USA.
Heidi HaapalaDepartment of Physical Medicine and Rehabilitation, 1259University of Michigan, Ann Arbor, MI, USA.

Funding

Addressing knowledge gaps by multi-level research design to optimize clinical trial development in order to reduce fracture burden for adults with neurodevelopmental disabilitiesR01AR076994 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HURVITZ, EDWARD A · 2021 to 2023
$616k
NIAMS NIH HHS R01 AR076994
6 · The paper itself

Abstract

objectiveRehabilitation may mitigate the high mortality rates and health declines post-fracture for adults with cerebral palsy, but this is understudied. The objectives were to characterize the post-fracture rehabilitation pathways and identify their association with 1-year survival among adults with cerebral palsy.

methodsA retrospective cohort study of adults with cerebral palsy with a fragility fracture with continuous health plan enrollment ≥1-year prior to and ≥1 day after their fracture date was performed using a random 20% Medicare fee-for-service dataset. Participants were categorized as a home discharge or inpatient rehabilitation admission post-fracture. For the home discharge cohort, weekly exposure to outpatient physical/occupational therapy (PT/OT) was examined up to 6-month post-fracture. Cox regression examined the association between time-varying PT/OTuse within 6-month post-fracture and mortality from 30 days to 1-year post-fracture before and after adjusting for confounders (e.g. medical complexity).

resultsOf 3598 adults with cerebral palsy with an incident fragility fracture, 74% were discharged home without inpatient rehabilitation; they were younger, but more medically complex compared to the 26% admitted to inpatient rehabilitation. Among the home discharge cohort (n = 2662), 43.1% initiated PT/OTwithin 6-month post-fracture, and cumulative PT/OTexposure post-fracture was associated with improved survival; for example, per 3 weeks of PT/OTexposure, the adjusted mortality rate was 40% lower (95% confidence interval (CI) = 0.41-0.89).

conclusionsMost adults with cerebral palsy with a fragility fracture were discharged home rather than to inpatient rehabilitation, and only 43.1% of that group initiated outpatient PT/OTwithin 6 months post-fracture. Receiving outpatient PT/OTwas associated with improved 1-year survival.

Indexed as

Cerebral PalsyFractures, BoneAdultAgedFee-for-Service PlansHumansMedicarePatient DischargeRetrospective StudiesUnited StatesCerebral palsyfracturerehabilitation interventions

Identifiers

PMID36039504
PMCPMC10150496

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.