Evidence map›Paper›PMID 36039467›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Survival Prediction in Home Hospice Care Patients with Lung Cancer Based on LASSO Algorithm.

Yicheng Zeng, Weihua Cao, Chaofen Wu, Muqing Wang, Yanchun Xie, Wenxia Chen, Xi Hu, Yanna Zhou, Xubin Jing, Xianbin Cai

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yicheng ZengDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Weihua CaoDepartment of Hospice, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Chaofen WuDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Muqing WangDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Yanchun XieDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Wenxia ChenDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Xi HuDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Yanna ZhouDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Xubin JingDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.
Xianbin CaiDepartment of Gastroenterology, 485866The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, P.R. China.ORCID https://orcid.org/0000-0002-3967-8666
Shantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the present study was to develop a nomogram for prognostic prediction of patients with lung cancer in hospice.

methodsThe data was collected from 1106 lung cancer patients in hospice between January 2008 and December 2018. The data were split into a training set, which was used to identify the most important prognostic factors by the least absolute shrinkage and selection operator (LASSO) and to build the nomogram, while the testing set was used to validate the nomogram. The performance of the nomogram was assessed by c-index, calibration curve and the decision curve analysis (DCA).

resultsA total of 1106 patients, including 835 (75%) from the training set and 271 (25%) from testing set, were retrospectively analyzed in this study. Using the LASSO regression, 5 most important prognostic predictors that included sex, Karnofsky Performance Scale (KPS), quality-of-life (QOL), edema and anorexia, were selected out of 28 variables. Validated c-indexes of training set at 15, 30, and 90 days were .778 [.737-.818], .776 [.743-.809], and .751 [.713-.790], respectively. Similarly, the validated c-indexes of testing set at 15, 30, and 90 days were .789 [.714-.864], .748 [.685-.811], and .757 [.691-.823], respectively. The nomogram-predicted survival was well calibrated, as the predicted probabilities were close to the expected probabilities. Moreover, the DCA curve showed that nomogram received superior standardized net benefit at a broad threshold.

conclusionsThe study built a non-lab nomogram with important predictor to analyze the clinical parameters using LASSO. It may be a useful tool to allow clinicians to easily estimate the prognosis of the patients with lung cancer in hospice.

Indexed as

Hospice CareHospicesLung NeoplasmsAlgorithmsHumansQuality of LifeRetrospective Studieshospice carelung cancermachine learningnomogramprognosis

Identifiers

PMID36039467
PMCPMC9434661
OpenAlexW4293659902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.