Evidence map›Paper›PMID 36039405›Full record

ArticleMolecular pain2022

Ginsenoside Rh2 Ameliorates Neuropathic Pain by inhibition of the miRNA21-TLR8-mitogen-activated protein kinase axis.

Yuan-Yuan Fu, Jian-Ke Cen, Hao-Lin Song, Si-Yuan Song, Zhi-Jun Zhang, Huan-Jun Lu

Open access · goldAbstract read
In one paragraph

Article in Molecular pain, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Brain plasticity and ginseng.Journal of ginseng research · 2024
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuan-Yuan FuInstitute of Pain Medicine and Special Environmental Medicine, Nantong University, Jiangsu, China.
Jian-Ke CenInstitute of Pain Medicine and Special Environmental Medicine, Nantong University, Jiangsu, China.
Hao-Lin SongDepartment of Human Anatomy, School of Medicine, Nantong University, Jiangsu, China.
Si-Yuan SongInstitute of Pain Medicine and Special Environmental Medicine, Nantong University, Jiangsu, China.
Zhi-Jun ZhangDepartment of Human Anatomy, School of Medicine, Nantong University, Jiangsu, China.
Huan-Jun LuInstitute of Pain Medicine and Special Environmental Medicine, Nantong University, Jiangsu, China.ORCID 0000-0001-6200-1437
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginsenoside Rh2 is one of the major bioactive ginsenosides in

Indexed as

GinsenosidesMicroRNAsNeuralgiaNeuroprotective AgentsAnalgesicsAnimalsAnti-Inflammatory AgentsExtracellular Signal-Regulated MAP KinasesHyperalgesiaInterleukin-6LigandsMiceRatsRats, Sprague-DawleyToll-Like Receptor 8Tumor Necrosis Factor-alphaAnalgesicsAnti-Inflammatory AgentsExtracellular Signal-Regulated MAP Kinasesginsenoside Rh2GinsenosidesInterleukin-6LigandsMicroRNAsmirn21 microRNA, ratNeuroprotective AgentsToll-Like Receptor 8Tumor Necrosis Factor-alphaChronic painGinsenoside Rh2miRNA-21spared nerve injuryTLR8

Identifiers

PMID36039405
PMCPMC9478689
OpenAlexW4293661005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.