ArticleInfection and drug resistance2022
Metagenomic Analysis of Urban Wastewater Treatment Plant Effluents in Tokyo.
Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Integrated qPCR and Shotgun Metagenomics for Surveillance of Antimicrobial Resistance in Municipal Wastewater from Central Italy.Antibiotics (Basel, Switzerland) · 2026Article
- The surveillance of antimicrobial resistance in wastewater from a one health perspective: A global scoping and temporal review (2014-2024).One health (Amsterdam, Netherlands) · 2025Article
- Effectiveness of Implementing Hospital Wastewater Treatment Systems as a Measure to Mitigate the Microbial and Antimicrobial Burden on the Environment.Antibiotics (Basel, Switzerland) · 2025Article
- Antimicrobial resistance transmission in the environmental settings through traditional and UV-enabled advanced wastewater treatment plants: a metagenomic insight.Environmental microbiome · 2025Article
- Bacterial Communities and Resistance and Virulence Genes in Hospital and Community Wastewater: Metagenomic Analysis.International journal of molecular sciences · 2025Article
- Comparative microbial metagenomic analysis of drinking water plants and wastewater treatment plants in Istanbul.Frontiers in microbiology · 2025Article
- Resistome analysis of wastewater treatment plants in Agadir city, Morocco, using a metagenomics approach.Scientific reports · 2024Article
- On-Site Inactivation for Disinfection of Antibiotic-Resistant Bacteria in Hospital Effluent by UV and UV-LED.Antibiotics (Basel, Switzerland) · 2024Article
- Article
- Performance of a Pilot-Scale Continuous Flow Ozone-Based Hospital Wastewater Treatment System.Antibiotics (Basel, Switzerland) · 2023Article
- Temporal disturbance of a model stream ecosystem by high microbial diversity from treated wastewater.MicrobiologyOpen · 2023Article
- Occurrence and Quantitative Microbial Risk Assessment of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Comprehensive Genome and Plasmidome Analysis of Antimicrobial Resistant Bacteria in Wastewater Treatment Plant Effluent of Tokyo.Antibiotics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Urban wastewater treatment plant (WWTP) effluents, even with proper treatment, may cause antimicrobial resistance (AMR) burden, with a high frequency of acquired antimicrobial resistance genes (ARGs). The dissemination of ARGs into the environment increases the risk of infectious diseases; however, there is little direct evidence regarding their epidemiological effects. This study aimed to assess effluents from urban WWTPs around the Tama River and Tokyo Bay using metagenomic analysis of (AMR) genes (ARGs) and heavy-metal resistance genes. Methods: Metagenomic DNA-seq analysis of water samples and resistome analysis were performed. Results: The most prevalent ARG was the sulfonamide resistance gene, Conclusion: We characterized a baseline level of the environmental ARG/HMRG profile in the overall community, suggesting that environmental AMR surveillance, particularly in urban WWTPs, is a valuable first step in monitoring the AMR dissemination of bacteria from predominantly healthy individuals carrying notable ARG/Bs.
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Registered trials
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