Evidence map›Paper›PMID 36038876›Full record

ReviewMicrobial cell factories2022

Advances in the human skin microbiota and its roles in cutaneous diseases.

Yudie Yang, Lingbo Qu, Ivan Mijakovic, Yongjun Wei

Open access · goldAbstract readReview
In one paragraph

Review in Microbial cell factories, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
22.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 113 citations in OpenAlex.

  1. Epithelial-Dermal Immune Memory: TrackingInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Skin bacteriota ameliorates androgenetic alopecia via harmonizing skin immuno inflammatory balance.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  6. Seed Oil ofInternational journal of molecular sciences · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Integration of Postbiotics into Adult Diapers:Life (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. The Microbiota-Human Health Axis.Microorganisms · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Yudie YangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450051, China.
Lingbo QuLaboratory of Synthetic Biology, Zhengzhou University, Zhengzhou, 450051, China.
Ivan MijakovicDepartment of Biology and Biological Engineering, Chalmers University of Technology, Göteborg, Sweden.
Yongjun WeiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450051, China. yongjunwei@zzu.edu.cn.
Zhengzhou University · CNChalmers University of Technology · SE

Funding

National Natural Science Foundation of China 32111530179Novo Nordisk Foundation NNF10CC1016517
6 · The paper itself

Abstract

Skin is the largest organ in the human body, and the interplay between the environment factors and human skin leads to some skin diseases, such as acne, psoriasis, and atopic dermatitis. As the first line of human immune defense, skin plays significant roles in human health via preventing the invasion of pathogens that is heavily influenced by the skin microbiota. Despite being a challenging niche for microbes, human skin is colonized by diverse commensal microorganisms that shape the skin environment. The skin microbiota can affect human health, and its imbalance and dysbiosis contribute to the skin diseases. This review focuses on the advances in our understanding of skin microbiota and its interaction with human skin. Moreover, the potential roles of microbiota in skin health and diseases are described, and some key species are highlighted. The prevention, diagnosis and treatment strategies for microbe-related skin diseases, such as healthy diets, lifestyles, probiotics and prebiotics, are discussed. Strategies for modulation of skin microbiota using synthetic biology are discussed as an interesting venue for optimization of the skin-microbiota interactions. In summary, this review provides insights into human skin microbiota recovery, the interactions between human skin microbiota and diseases, and the strategies for engineering/rebuilding human skin microbiota.

Indexed as

Dermatitis, AtopicMicrobiotaSkin DiseasesDysbiosisHumansSkinAcneCommensal microbesCutaneous diseasesHost-skin microbiota interactionMicrobiotaOmics technologiesSkinSynthetic biology

Identifiers

PMID36038876
PMCPMC9422115
OpenAlexW4293441691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.