ArticleEye (London, England)2023
Detection ability of corneal biomechanical parameters for early diagnosis of ectasia.
Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Prevalence and Risk Factors for Keratoconus in Young Adults Assessed with Tomography and Corneal Biomechanics: A Prospective Cross-Sectional Study.Ophthalmology science · 2026Article
- Analysis of corneal biomechanical characteristics and clinical correlations in children with dust mite-allergic conjunctivitis.Scientific reports · 2026Article
- Challenges in Glaucoma Management in High Myopia After Refractive Surgery: A Case Report.Cureus · 2026Article
- Waveform Score Influences the Outcome Metrics of the Ocular Response Analyzer in Patients with Keratoconus and in Healthy Controls.Current eye research · 2025Article
- Early diagnosis of keratoconus using corneal biomechanics and OCT derived technologies.Eye and vision (London, England) · 2025Review
- Multi-modal imaging for the detection of early keratoconus: a narrative review.Eye and vision (London, England) · 2024Review
- Comparison of corneal biomechanical parameters in healthy corneas with symmetric and asymmetric bow-tie topographic pattern with inferior and superior steepening.International ophthalmology · 2024Article
- Refractive associations with corneal biomechanical properties among young adults: a population-based Corvis ST study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Characterization of Corneal Biomechanics Using CORVIS ST Device in Different Grades of Myopia in a Sample of Middle Eastern Ethnicity.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Changes in Stress-Strain Index and Corneal Biomechanics in Granular Corneal Dystrophy.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the detection ability of corneal biomechanical parameters for early diagnosis of ectasia.
methodsThis retrospective descriptive-analytical study included 134 normal eyes (control group) from 134 healthy subjects and 128 eyes with asymmetric contralateral corneal ectasia with normal topography (ACE-NT, study group) from 128 subjects with definite keratoconus in the opposite eye. Placido-disk-based corneal topography with TMS-4, Scheimpflug corneal tomography with Pentacam HR, and corneal biomechanical assessment with Corvis ST and ocular response analyzer (ORA) were performed. A general linear model was used to compare Corvis ST and ORA biomechanical parameters between groups, while central corneal thickness (CCT) and biomechanically corrected intraocular pressure (bIOP) were considered covariates. Receiving operator sensitivity curve (ROC) analysis was used to determine the cut-off point with the highest sensitivity and specificity along with the area under the curve (AUC) for each parameter.
resultAll parameters of Corvis ST and ORA showed a statistically significant difference between the two groups except for the first (P = 0.865) and second (P = 0.226) applanation lengths, and deformation amplitude (P = 0.936). The discriminative analysis of corneal biomechanical showed that the highest accuracy for the classic, new, and combined parameters of Corvis ST was related to HCR (AUC: 0.766), IR & DAR (0.846), and TBI (0.966), respectively. Using ORA, the corneal resistance factor (0.866) had a higher detection ability than corneal hysteresis (0.826).
conclusionsTBI has the best accuracy and the highest effect size for differential diagnosis of normal from ACE-NT eyes with a cut-off point of 0.24.
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