Evidence map›Paper›PMID 36038138›Full record

ArticleACS chemical biology2022

Ashleigh S Paparella, Sean M Cahill, Briana L Aboulache, Vern L Schramm

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. AgainstToxins · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ashleigh S PaparellaDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Sean M CahillDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Briana L AboulacheDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Vern L SchrammDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.ORCID 0000-0002-8056-1929
Albert Einstein College of Medicine · US

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2M
TRANSITION STATE ANALYSIS OF ENZYMATIC REACTIONSR01GM041916 · NIGMS · YESHIVA UNIVERSITY · PI SCHRAMM, VERN L. · 1989 to 2023
$10.0M
TRANSITION STATE ANALYSIS OF ENZYMATIC REACTIONSR37GM041916 · NIGMS · YESHIVA UNIVERSITY · PI SCHRAMM, VERN L. · 1998 to 2007
$3.5M
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxinsR01AI150971 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SCHRAMM, VERN L. · 2021 to 2025
$3.3M
NCI NIH HHS P30 CA013330NIAID NIH HHS R01 AI150971NIGMS NIH HHS R01 GM041916NIGMS NIH HHS R37 GM041916
6 · The paper itself

Abstract

Toxins TcdA and TcdB from

Indexed as

Bacterial ToxinsClostridioides difficileBacterial ProteinsGlucoseGlucosyltransferasesHumansKineticsPhosphatesrho GTP-Binding ProteinsTetanus ToxinThreonineUridine Diphosphate GlucoseBacterial ProteinsBacterial ToxinsGlucoseGlucosyltransferasesPhosphatesrho GTP-Binding ProteinsTetanus ToxinThreonineUridine Diphosphate Glucose

Identifiers

PMID36038138
PMCPMC9486934
OpenAlexW4293510191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.