Evidence map›Paper›PMID 36037476›Full record

ArticleJournal of virology2022

Establishment and Characterization of an HBV Viral Spread and Infectious System following Long-Term Passage of an HBV Clinical Isolate in the Primary Human Hepatocyte and Fibroblast Coculture System.

Yang Liu, Dmytro Kornyeyev, Lindsey May, Dong Han, Thomas Aeschbacher, Silvia Chang, Ross Martin, Hongmei Mo, Becket Feierbach

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. [Construction of a highly efficient HBV infection cell model based on HBV co-receptor neuropilin-1].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  2. Article
  3. Relevance of HBx for Hepatitis B Virus-Associated Pathogenesis.International journal of molecular sciences · 2023
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yang LiuGilead Sciences, Inc., Foster City, California, USA.ORCID 0000-0001-8095-2009
Dmytro KornyeyevGilead Sciences, Inc., Foster City, California, USA.
Lindsey MayGilead Sciences, Inc., Foster City, California, USA.
Dong HanGilead Sciences, Inc., Foster City, California, USA.
Thomas AeschbacherGilead Sciences, Inc., Foster City, California, USA.
Silvia ChangGilead Sciences, Inc., Foster City, California, USA.
Ross MartinGilead Sciences, Inc., Foster City, California, USA.
Hongmei MoGilead Sciences, Inc., Foster City, California, USA.
Becket FeierbachGilead Sciences, Inc., Foster City, California, USA.
Gilead Sciences (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The existing cell culture-based methods to study hepatitis B virus (HBV) have limitations and do not allow for viral long-term passage. The aim of this study was to develop a robust

Indexed as

Coculture TechniquesHepatitis BHepatitis B virusVirologyDNA, ViralFibroblastsGenotypeHepatocytesHumansMutagenesisMutationVirus ReplicationDNA, Viralbasal core promoter mutationIn vitro HBV spread and passageprimary human hepatocyte and fibroblast coculture

Identifiers

PMID36037476
PMCPMC9517703
OpenAlexW4293731259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.