Evidence map›Paper›PMID 36037386›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses.

Shinsuke Toba, Akihiko Sato, Makoto Kawai, Yoshiyuki Taoda, Yuto Unoh, Shinji Kusakabe, Haruaki Nobori, Shota Uehara, Kentaro Uemura, Keiichi Taniguchi and 17 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Pharmacophores of Influenza Virus PA Endonuclease Inhibitors.Advances in experimental medicine and biology · 2026
    Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 6 institutions in 3 countries.

Shinsuke TobaShionogi & Co., Ltd., Osaka 561-0825, Japan.ORCID 0000-0001-6185-1587
Akihiko SatoShionogi & Co., Ltd., Osaka 561-0825, Japan.ORCID 0000-0001-6625-1679
Makoto KawaiShionogi & Co., Ltd., Osaka 561-0825, Japan.
Yoshiyuki TaodaShionogi & Co., Ltd., Osaka 561-0825, Japan.ORCID 0000-0001-8469-3788
Yuto UnohShionogi & Co., Ltd., Osaka 561-0825, Japan.
Shinji KusakabeShionogi & Co., Ltd., Osaka 561-0825, Japan.ORCID 0000-0002-1860-6049
Haruaki NoboriShionogi & Co., Ltd., Osaka 561-0825, Japan.
Shota UeharaShionogi & Co., Ltd., Osaka 561-0825, Japan.ORCID 0000-0001-5214-8531
Kentaro UemuraShionogi & Co., Ltd., Osaka 561-0825, Japan.
Keiichi TaniguchiShionogi & Co., Ltd., Osaka 561-0825, Japan.
Masanori KobayashiShionogi & Co., Ltd., Osaka 561-0825, Japan.
Takeshi NoshiShionogi & Co., Ltd., Osaka 561-0825, Japan.
Ryu YoshidaShionogi & Co., Ltd., Osaka 561-0825, Japan.
Akira NaitoShionogi & Co., Ltd., Osaka 561-0825, Japan.ORCID 0000-0003-4119-6735
Takao ShishidoShionogi & Co., Ltd., Osaka 561-0825, Japan.
Junki MaruyamaDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555.ORCID 0000-0003-0088-4793
Slobodan PaesslerDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555.ORCID 0000-0002-2213-9551
Michael J CarrInternational Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.ORCID 0000-0003-0011-6209
William W HallInternational Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.ORCID 0000-0001-7560-3808
Kumiko YoshimatsuLaboratory of Animal Experimentation, Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido 060-0815, Japan.ORCID 0000-0002-0062-2753
Jiro ArikawaOffice for Biosafety Auditor, Nagasaki University, Nagasaki 852-8521, Japan.ORCID 0000-0001-8870-6494
Keita MatsunoInternational Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.
Yoshihiro SakodaDepartment of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.
Michihito SasakiDivision of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.ORCID 0000-0003-1607-2175
Yasuko OrbaDivision of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.
Hirofumi SawaDivision of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.ORCID 0000-0003-2569-2755
Hiroshi KidaInternational Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.ORCID 0000-0003-4876-1004
Hokkaido University · JPShionogi (Japan) · JPHealth Sciences University of Hokkaido · JPThe University of Texas Medical Branch at Galveston · USUniversity College Dublin · IEUniversity of Nagasaki · JP

Funding

Viral factors responsible for Lassa virus pathogenicityR00AI156012 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MARUYAMA, JUNKI · 2023 to 2024
$498k
Viral factors responsible for Lassa virus pathogenicityK99AI156012 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MARUYAMA, JUNKI · 2021 to 2022
$177k
NIAID NIH HHS K99 AI156012NIAID NIH HHS R00 AI156012
6 · The paper itself

Abstract

Viral hemorrhagic fevers caused by members of the order

Indexed as

Antiviral AgentsEndonucleasesOrthobunyavirusAnimalsDrug Evaluation, PreclinicalDrug Resistance, ViralHumansMiceVirus ReplicationAntiviral AgentsEndonucleasesantiviral compoundsbunyaviruscap-dependent endonuclease

Identifiers

PMID36037386
PMCPMC9457168
OpenAlexW4293484180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.