ArticleAsian Pacific journal of cancer prevention : APJCP2022
The Relationship between Unmet Need, Physical Symptoms, Psychological Well-Being and Health-Related Quality of Life in Cholangiocarcinoma Survivors.
Article in Asian Pacific journal of cancer prevention : APJCP, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Quality of Life Among Thai Patients With Advanced Cancer: Findings From the APPROACH Study.Asia-Pacific journal of clinical oncology · 2026Article
- Inflammation-associated depression in cholangiocarcinoma: impacts of surgical resection and radiotherapy.BioPsychoSocial medicine · 2026Article
- A review, evaluation and content mapping study of Australian patient-facing online pancreatobiliary cancer resources.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Review
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCholangiocarcinoma (CCA) survivors continue to face challenges that affect their health-related quality of life (HRQOL) along the survivorship trajectory.
objectiveThis study intends to investigate the association and to create a model for explaining the link between unmet needs, physical symptoms, psychological well-being, and HRQOL in CCA survivors.
methodThis cross-sectional study consecutively recruited 231CCA survivors from an oncology unit of a university hospital in Khon Kaen, Thailand. Cancer-related unmet need, physical symptoms, psychological well-being and HRQOL were all assessed using the questionnaire, and medical records were used to acquire demographic and clinical data. We use a path analysis to create a hypothesized model in which symptoms, unmet need, anxiety, and depression, support care need predicting HRQOL.
resultsThe mean total of HRQOL score was 75.59±6.24 (95%CI: 74.78-76.39) indicated that the subjects had a low level of HRQOL as a whole. The hypothesis model was found to fit the actual data and explained 39.8% of the variance of HRQOL. Symptoms and anxiety had a significant negative effect on HRQOL (β = -0.62, p< 0.001) and (β=-0.18, p<0.001), respectively. However, the relationship between HRQOL and other mediators was not found significant association.
conclusionAccording to our findings, the research model can be used to investigate how symptoms affect HRQOL. It also means that cancer care providers should be aware of these factors while caring for CCA survivors in order to enhance their HRQOL.
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