Evidence map›Paper›PMID 36036936›Full record

Trial reportJAMA network open2022

Remdesivir in Patients With Severe Kidney Dysfunction: A Secondary Analysis of the CATCO Randomized Trial.

Matthew Cheng, Rob Fowler, Srinivas Murthy, Ruxandra Pinto, Nancy L Sheehan, Alice Tseng

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in JAMA network open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04330690 (A Multi-centre, Adaptive, Randomized, Open-label, Controlled Clinical Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Patients), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04330690 phase3unknown statusnot on this map

A Multi-centre, Adaptive, Randomized, Open-label, Controlled Clinical Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Patients (CATCO: Canadian Treatments for COVID-19), in Conjunction With the Public Health Emergency SOLIDARITY Trial (World Health Organization)

TypeinterventionalSponsorSunnybrook Health Sciences CentreRan2020 to 2024Enrolled2,900ConditionsCOVID-19ArmsArtesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Remdesivir in COVID-19: pros and cons.Frontiers in pharmacology · 2026
    Review
  3. Long COVID and the kidney.Nature reviews. Nephrology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. COVID-19 therapeutics.Clinical microbiology reviews · 2024
    Review
  9. COVID-19: On the threshold of the fifth year. The situation in Spain.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Treatment of Severe COVID-19 Infection With Remdesivir in Peritoneal Dialysis.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Matthew ChengMcGill University Health Centre, Montréal, Québec, Canada.
Rob FowlerSunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Srinivas MurthyFaculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Ruxandra PintoSunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Nancy L SheehanMcGill University Health Centre, Montréal, Québec, Canada.
Alice TsengUniversity Health Network, Toronto General Hospital, Toronto, Ontario, Canada.
McGill University Health Centre · CAHealth Sciences Centre · CASunnybrook Health Science Centre · CAToronto General Hospital · CAUniversity of British Columbia · CA

Funding

CIHR
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlanineKidneyKidney DiseasesAdenosine MonophosphateHumansAdenosine MonophosphateAlanineremdesivir

Identifiers

PMID36036936
PMCPMC9425145
OpenAlexW4293458534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.