ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2023
Comparison of outcomes and operative course between septic and aseptic nonunion in long bones.
Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Risk factors for delayed healing and multiple revisions in humeral shaft nonunion: a retrospective case series.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Treatment of Post-Traumatic Diaphyseal and Distal Tibial Bone Defects by Distraction Osteogenesis: A Monocentric Experience.Journal of clinical medicine · 2025Article
- Management of chronic septic nonunion of the femur associated with an extended drug-resistant nosocomial germ: a case report.Annals of medicine and surgery (2012) · 2025Article
- Distal femoral bone defect treatment using an engineered hydroxyapatite cylinder scaffold made from rattan wood.BMJ case reports · 2025Article
- Treatment of infected humeral shaft nonunion and presumed aseptic nonunion with positive intraoperative cultures: a retrospective single-center study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Management of aseptic nonunions of bicondylar tibial plateau fractures.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Risk factors and healthcare costs associated with long bone fracture non-union: a retrospective US claims database analysis.Journal of orthopaedic surgery and research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe treatment of nonunion of long bones is difficult particularly in the presence of infection, which often involves staged surgical management. There is limited literature to compare the post operative course and outcomes of patients treated for septic versus aseptic nonunion. Thus, the purpose of this study was to determine if a difference exists between the number of surgical procedures, time to union, and rate of successful union for these two groups.
methodsA retrospective cohort study was performed at a single tertiary care center. Patients suffering nonunion of the humerus, tibia and femur were included. Patient demographic data and characteristics of the post operative course were collected to include number and reason for repeat operations, antibiotic course, time to union, and development of a successful union.
resultsAbout 28 of 122 patients had septic nonunion. After diagnosis of nonunion, the septic group averaged 3.9 surgeries compared to 1.5 in the aseptic group (p < 0.001). There was no difference in the rate of successful union (79.8% versus 85.7%; p = 0.220), though the septic group took 129 days longer on average for successful union. (376 versus 247; p = 0.018).
conclusionSeptic nonunion of long bones is associated with the need for significantly more operations as well as time to union, though union rates remain similar. The identification of infection is critical for both the appropriate treatment as well as counseling patients on the expected post operative course.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.