ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023
Rate and nature of complications with leadless transcatheter pacemakers compared with transvenous pacemakers: results from an Italian multicentre large population analysis.
Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06656468 (Outcome of Patients Undergoing Leadless Pacemaker Implantaton), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Outcome of Patients Undergoing Leadless Pacemaker Implantaton
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Success and complication rates of conduction system pacing: a meta-analytical observational comparison of left bundle branch area pacing and His bundle pacing.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Pooled it
- Two-year outcomes of leadless vs. transvenous single-chamber ventricular pacemaker in high-risk subgroups.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Trial
- Comparison of Outcomes of Leadless Versus Transvenous Pacemakers Following Tricuspid Valve Surgery.Journal of the American Heart Association · 2026Article
- Leadless pacing-induced pacemaker syndrome managed with atrial leadless pacing device.HeartRhythm case reports · 2026Article
- Leadless Pacemaker for Sinus Pauses and Syncope in Pregnancy: A Feasible Alternative to Conventional Pacing.The Journal of innovations in cardiac rhythm management · 2026Article
- Association Between Septal Implantation Level and Pacing Threshold Stability in Leadless Pacemaker Implantation.Journal of clinical medicine · 2026Article
- Leadless Pacemakers in Complex Congenital Heart Disease.Journal of clinical medicine · 2025Review
- Micra leadless pacemaker revisions: incidence, characteristics, and outcomes from a multicentre French cohort.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Leadless vs. transvenous pacemakers following transcatheter aortic valve replacement: a dual-centre propensity score-matched observational study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Leadless vs. Transvenous Pacemakers in Patients with End-Stage Renal Disease: A Systematic Review and Meta-Analysis.Biomedicines · 2025Review
- A case report on the implantation of a leadless pacemaker in a patient with eosinophilic fasciitis and third-degree atrioventricular block.BMC cardiovascular disorders · 2025Article
- Leadless pacemaker implantation in real-world clinical practice: An Italian survey promoted by the AIAC (Italian Association of Arrhythmology and Cardiac Pacing).Journal of arrhythmia · 2025Article
- Leadless pacing in young patients.European heart journal supplements : journal of the European Society of Cardiology · 2025Article
- Comparative safety of transvenous and leadless pacemakers in patients with cardiovascular diseases: A meta-analysis study.Heliyon · 2025Article
- Feasibility of Echocardiography-guided Percutaneous Transapical Lead Implantation for Intraventricular Septal Pacing: Acute and 3-Month Evaluation.Arrhythmia & electrophysiology review · 2025Article
- Atrial Fibrillation and Cancer-Epidemiology, Mechanisms, and Management.Journal of clinical medicine · 2024Review
- Impact of body mass index on in-hospital outcomes in patients receiving leadless pacemakers: A five-category analysis.Heart rhythm O2 · 2024Article
- A rate-responsive duty-cycling protocol for leadless pacemaker synchronization.Biomedical engineering letters · 2024Article
- Tissue-induced winding of permanent pacemaker passive-fixation leads.Quantitative imaging in medicine and surgery · 2023Article
- Comparison of Safety of Leadless Pacemakers and Transvenous Pacemakers: A Meta-Analysis.Cureus · 2023Review
Corrections and comments
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Authors and funding
13 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe safety and efficacy of leadless intracardiac-permanent pacemaker (L-PM) have been demonstrated in multiple clinical trials, but data on comparisons with conventional transvenous-permanent pacemaker (T-PM) collected in a consecutive, prospective fashion are limited. The aim of this analysis was to compare the rate and the nature of device-related complications between patients undergoing L-PM vs. T-PM implantation. METHODS AND
resultsProspective, multicentre, observational project enrolling consecutive patients who underwent L-PM or T-PM implantation. The rate and nature of device-related complications were analysed and compared between the two groups. Individual 1:1 propensity matching of baseline characteristics was performed. A total of 2669 (n = 665 L-PM) patients were included and followed for a median of 39 months, L-PM patients were on average older and had more co-morbidities. The risk of device-related complications at 12 months was significantly lower in the L-PM group (0.5% vs. 1.9%, P = 0.009). Propensity matching yielded 442 matched pairs. In the matched cohort, L-PM patients trended toward having a lower risk of overall device-related complications (P = 0.129), had a similar risk of early complications (≤30 days) (P = 1.000), and had a significantly lower risk of late complications (>30 days) (P = 0.031). All complications observed in L-PM group were early. Most (75.0%) of complications observed in T-PM group were lead- or pocket-related.
conclusionIn this analysis, the risk of device-related complications associated with L-PM implantation tended to be lower than that of T-PM. Specifically, the risk of early complications was similar in two types of PMs, while the risk of late complications was significantly lower for L-PM than T-PM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.