Evidence map›Paper›PMID 36036586›Full record

ArticleApplied and environmental microbiology2022

Precise Regulation of Differential Transcriptions of Various Catabolic Genes by OdcR via a Single Nucleotide Mutation in the Promoter Ensures the Safety of Metabolic Flux.

Kai Chen, Zhuang Ke, Sicheng Wang, Shen Wang, Ke Yang, Weibin Jia, Jianchun Zhu, Jiandong Jiang

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kai ChenDepartment of Microbiology, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing, China.
Zhuang KeDepartment of Microbiology, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing, China.
Sicheng WangDepartment of Microbiology, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing, China.
Shen WangDepartment of Microbiology, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing, China.
Ke YangDepartment of Microbiology, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing, China.
Weibin JiaDepartment of Microbiology, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing, China.
Jianchun ZhuLaboratory Centre of Life Sciences, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.
Jiandong JiangDepartment of Microbiology, College of Life Sciences, Nanjing Agricultural Universitygrid.27871.3b, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing, China.ORCID 0000-0003-4877-5756
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synergistic regulation of the expression of various genes in a catabolic pathway is crucial for the degradation, survival, and adaptation of microorganisms in polluted environments. However, how a single regulator accurately regulates and controls differential transcriptions of various catabolic genes to ensure metabolic safety remains largely unknown. Here, a LysR-type transcriptional regulator (LTTR), OdcR, encoded by the regulator gene

Indexed as

AlcaligenaceaeGene Expression Regulation, BacterialBacterial ProteinsDeoxyribonuclease IMutationNucleotidesBacterial ProteinsDeoxyribonuclease INucleotides2,6-dibromohydroquinone toxicity3,5-dibromo-4-hydroxybenzoateactivatordifferential transcriptionLysR-type transcriptional regulatormetabolic safety

Identifiers

PMID36036586
PMCPMC9499029
OpenAlexW4293446681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.