Evidence map›Paper›PMID 36036373›Full record

ReviewJournal of applied microbiology2022

Antimicrobial betalains.

Vindya Nilakshi Wijesinghe, Wee Sim Choo

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Microorganisms · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Frontiers in chemistry · 2023
    Review
  13. Antimicrobial betalains.Journal of applied microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vindya Nilakshi WijesingheSchool of Science, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.
Wee Sim ChooSchool of Science, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.ORCID https://orcid.org/0000-0003-0495-3303
Monash University Malaysia · MY

Funding

Ministry of Higher Education Malaysia FRGS/1/2020/SKK0/MUSM/02/1
6 · The paper itself

Abstract

Betalains are nitrogen-containing plant pigments that can be red-violet (betacyanins) or yellow-orange (betaxanthins), currently employed as natural colourants in the food and cosmetic sectors. Betalains exhibit antimicrobial activity against a broad spectrum of microbes including multidrug-resistant bacteria, as well as single-species and dual-species biofilm-producing bacteria, which is highly significant given the current antimicrobial resistance issue reported by The World Health Organization. Research demonstrating antiviral activity against dengue virus, in silico studies including SARS-CoV-2, and anti-fungal effects of betalains highlight the diversity of their antimicrobial properties. Though limited in vivo studies have been conducted, antimalarial and anti-infective activities of betacyanin have been observed in living infection models. Cellular mechanisms of antimicrobial activity of betalains are yet unknown; however existing research has laid the framework for a potentially novel antimicrobial agent. This review covers an overview of betalains as antimicrobial agents and discussions to fully exploit their potential as therapeutic agents to treat infectious diseases.

Indexed as

Anti-Infective AgentsCOVID-19 Drug TreatmentBetacyaninsBetalainsHumansSARS-CoV-2Anti-Infective AgentsBetacyaninsBetalainsantibacterialantibiofilmanti-fungalantiviralbetacyaninESKAPE pathogens

Identifiers

PMID36036373
PMCPMC9826318
OpenAlexW4293441081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.