Evidence map›Paper›PMID 36036242›Full record

ArticleGut microbes

Camille Martin-Gallausiaux, Diego Garcia-Weber, Amandine Lashermes, Pierre Larraufie, Ludovica Marinelli, Veronica Teixeira, Alice Rolland, Fabienne Béguet-Crespel, Vincent Brochard, Timothé Quatremare and 6 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. The role ofFrontiers in medicine · 2025
    Pooled it
  2. Gut microbes · 2026
    Article
  3. Gut microbes · 2026
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  4. Gut microbes · 2026
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  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
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  13. Effects of Melatonin andAntioxidants (Basel, Switzerland) · 2026
    Article
  14. Article
  15. Polysaccharide fromFoods (Basel, Switzerland) · 2026
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Camille Martin-GallausiauxINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.ORCID 0000-0002-6193-4304
Diego Garcia-WeberINSERM, Institut Cochin, Université de Paris Cité, CNRS, Paris, France.ORCID 0000-0001-9170-5695
Amandine LashermesINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.
Pierre LarraufieINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.ORCID 0000-0001-7718-6200
Ludovica MarinelliINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.ORCID 0000-0002-2995-5105
Veronica TeixeiraINSERM, Institut Cochin, Université de Paris Cité, CNRS, Paris, France.
Alice RollandINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.
Fabienne Béguet-CrespelINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.
Vincent BrochardINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.
Timothé QuatremareINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.
Alexandre JametINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.
Joël DoréINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.ORCID 0000-0002-8756-0718
Scott D Gray-OwenDepartment of Molecular Genetics, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1477-3616
Hervé M BlottièreINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.ORCID 0000-0002-8390-0607
Cécile ArrieumerlouINSERM, Institut Cochin, Université de Paris Cité, CNRS, Paris, France.ORCID 0000-0002-6463-2897
Nicolas LapaqueINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.ORCID 0000-0003-0824-0108
AgroParisTech · FRCentre National de la Recherche Scientifique · FRUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The commensal bacteria that make up the gut microbiota impact the health of their host on multiple levels. In particular, the interactions taking place between the microbe-associated molecule patterns (MAMPs) and pattern recognition receptors (PRRs), expressed by intestinal epithelial cells (IECs), are crucial for maintaining intestinal homeostasis. While numerous studies showed that TLRs and NLRs are involved in the control of gut homeostasis by commensal bacteria, the role of additional innate immune receptors remains unclear. Here, we seek for novel MAMP-PRR interactions involved in the beneficial effect of the commensal bacterium

Indexed as

Gastrointestinal MicrobiomeNF-kappa BAdenosine DiphosphateAkkermansiaHeptosesImmunity, InnateTNF Receptor-Associated Factor 6VerrucomicrobiaAdenosine DiphosphateHeptosesNF-kappa BTNF Receptor-Associated Factor 6akkermansia muciniphilaALPK1intestinal epithelial cellsMicrobiotaNF-κB

Identifiers

PMID36036242
PMCPMC9427033
OpenAlexW4293531404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.