Evidence map›Paper›PMID 36036237›Full record

ArticleClinical and translational allergy2022

Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response.

Elise M A Slob, Alen Faiz, Jos van Nijnatten, Susanne J H Vijverberg, Cristina Longo, Merve Kutlu, Fook Tim Chew, Yang Yie Sio, Esther Herrera-Luis, Antonio Espuela-Ortiz and 26 more

Abstract readLetter
In one paragraph

Article in Clinical and translational allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Elise M A SlobDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-8411-7825
Alen FaizDepartment of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands.
Jos van NijnattenDepartment of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands.
Susanne J H VijverbergDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Cristina LongoDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Merve KutluDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Fook Tim ChewDepartment of Biological Science, National University of Singapore, Singapore, Singapore.
Yang Yie SioDepartment of Biological Science, National University of Singapore, Singapore, Singapore.
Esther Herrera-LuisGenomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.ORCID https://orcid.org/0000-0003-4150-5454
Antonio Espuela-OrtizGenomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.
Javier Perez-GarciaGenomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.ORCID https://orcid.org/0000-0001-7813-4381
Maria Pino-YanesGenomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.
Esteban G BurchardDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.
Uroš PotočnikCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Mario GorenjakCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Colin PalmerPopulation Pharmacogenetics Group, Biomedical Research Institute, University of Dundee, Dundee, UK.
Cyrielle MaroteauPopulation Pharmacogenetics Group, Biomedical Research Institute, University of Dundee, Dundee, UK.
Steve TurnerChild Health, University of Aberdeen, Aberdeen, UK.
Katia VerhammeDepartment of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands.
Leila KarimiDepartment of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-1746-3314
Somnath MukhopadhyayDepartment of Paediatrics, Royal Alexandra Children's Hospital, Brighton, UK.
Wim TimensDepartment of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands.
Pieter S HiemstraDepartment of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
Mariëlle W PijnenburgDepartment of Pediatrics, Pediatric Pulmonology and Allergology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Margaret NeighborsOMNI Biomarker Development, Genentech Inc, South San Francisco, California, USA.
Michele A GrimbaldestonOMNI Biomarker Development, Genentech Inc, South San Francisco, California, USA.
Gaik W TewProduct Development Immunology, Infectious Disease & Ophtalmology, Genentech Inc, South San Francisco, California, USA.
Corry A BrandsmaDepartment of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands.
Vojko BerceCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Hananeh AlieeInstitute of Computational Biology, Helmholtz Center, Munich, Germany.
Fabian TheisInstitute of Computational Biology, Helmholtz Center, Munich, Germany.
Don D SinCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.
Xuan LiCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.
Maarten van den BergeDepartment of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands.
Anke H Maitland-van der ZeeDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Gerard H KoppelmanUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands.

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
Social Interventions to address disparities In young adult tobacco useP60MD006902 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$6.4M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
SF BUILD: Enabling Students to Represent in ScienceRL5GM118984 · NIGMS · SAN FRANCISCO STATE UNIVERSITY · PI MARQUEZ-MAGANA, LETICIA MARIA, MORRIS, MEGHAN D · 2015 to 2023
$5.2M
Optimizing imputation for diverse populations in a distributed frameworkU01HG009080 · NHGRI · STANFORD UNIVERSITY · PI KENNY, EIMEAR ELIZABETH · 2016 to 2020
$5.2M
Transcriptomic and Pharmacogenetic Asthma Endotypes in Minority ChildrenR01HL135156 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A, ZIV, ELAD · 2017 to 2021
$4.1M
Genes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8M
Genetic Control of Airway Epithelium Gene Expression in Childhood AsthmaticsR01HL128439 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A · 2015 to 2019
$3.1M
Poly-omic Study of Asthma Exacerbations in Diverse PopulationsR01HL141845 · NHLBI · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2019 to 2022
$3.0M
Integrative Analyses to Uncover Biological Mechanisms Mediating Gene Associations with Asthma Drug Response Among Minority ChildrenR01HL141992 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI BURCHARD, ESTEBAN GONZALEZ, HIMES, BLANCA E · 2018 to 2019
$855k
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse ChildrenR21ES024844 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, GAUDERMAN, WILLIAM JAMES · 2015 to 2017
$509k
American Asthma FoundationCellarity, Inc.DermagnostixEuropean Regional Development FundGenentechGlaxoSmithKlineHarry Wm. and Diana V. Hind Distinguished Professor in Pharmaceutical Sciences IIInstituto de Salud Carlos IIILeids Universitair Medisch CentrumLongfondsMinisterio de Ciencia e InnovaciónMinistry of Education, Science and Sport SloveniaNational Institute of Health and Environmental HealthNCATS NIH HHS UL1 TR001872Nederlandse Organisatie voor Wetenschappelijk OnderzoekNHGRI NIH HHS U01 HG009080NHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01 HL128439NHLBI NIH HHS R01 HL135156NHLBI NIH HHS R01 HL141845NHLBI NIH HHS R01 HL141992NIEHS NIH HHS R01 ES015794NIEHS NIH HHS R21 ES024844NIGMS NIH HHS RL5 GM118984NIMHD NIH HHS P60 MD006902NIMHD NIH HHS R01 MD010443NIMHD NIH HHS R56 MD013312Roche DiagnosticsRWJF Amos Medical Faculty Development ProgramSandler Family FoundationSlovenian Research AgencyStichting Astma BestrijdingTobacco-Related Disease Research ProgramUniversitair Medisch Centrum GroningenUtrecht Institute for Pharmaceutical Sciences
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

childrenexacerbationsinhaled corticosteroidsmethylation quantitative trait loci (meQTL)pharmacogenetics

Identifiers

PMID36036237
PMCPMC9421427

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.