Evidence map›Paper›PMID 36035986›Full record

ArticleFrontiers in cell and developmental biology2022

Albumin-Based Nanocarriers for the Simultaneous Delivery of Antioxidant Gene and Phytochemical to Combat Oxidative Stress.

Saba Naqvi, Vitaly A Khanadeev, Boris N Khlebtsov, Nikolai G Khlebtsov, Monika S Deore, Gopinath Packirisamy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Sulforaphane and ophthalmic diseases.Food science & nutrition · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saba NaqviDepartment of Regulatory Toxicology/Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Raebareli, India.
Vitaly A KhanadeevInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia.
Boris N KhlebtsovInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia.
Nikolai G KhlebtsovInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia.
Monika S DeoreDepartment of Regulatory Toxicology/Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Raebareli, India.
Gopinath PackirisamyNanobiotechnology Laboratory, Department of Biosciences and Bioengineering, Joint Faculty in Centre for Nanotechnology, Indian Institute of Technology Roorkee, Roorkee, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human serum albumin (HSA) nanoparticles are promising biocompatible, nontoxic, and non-immunogenic platforms for biomedical applications such as bioimaging and drug and gene delivery. The development of nonviral gene delivery vectors is a great challenge for efficient and safe gene therapy. Sulforaphane (SF) can stimulate the expression of antioxidant genes

Indexed as

antioxidant activityhuman serum albumin (HSA)L-132 cellspSOD1 plasmidsulforaphane

Identifiers

PMID36035986
PMCPMC9412823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.