Evidence map›Paper›PMID 36035945›Full record

ArticleFrontiers in cardiovascular medicine2022

Exploration of cerebral hemodynamic pathways through which large artery function affects neurovascular coupling in young women.

Burak T Cilhoroz, Jacob P DeBlois, Wesley K Lefferts, Allison P Keller, Patricia Pagan Lassalle, Michelle L Meyer, Lee Stoner, Kevin S Heffernan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Burak T CilhorozDepartment of Exercise Science, Syracuse University, Syracuse, NY, United States.
Jacob P DeBloisDepartment of Exercise Science, Syracuse University, Syracuse, NY, United States.
Wesley K LeffertsDepartment of Kinesiology, Iowa State University, Ames, IA, United States.
Allison P KellerDepartment of Exercise Science, Syracuse University, Syracuse, NY, United States.
Patricia Pagan LassalleDepartment of Exercise and Sport Science, University of North Carolina, Chapel Hill, NC, United States.
Michelle L MeyerDepartment of Epidemiology, Gilling's School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Lee StonerDepartment of Exercise and Sport Science, University of North Carolina, Chapel Hill, NC, United States.
Kevin S HeffernanDepartment of Exercise Science, Syracuse University, Syracuse, NY, United States.
Syracuse University · USUniversity of North Carolina at Chapel Hill · USIowa State University · US

Funding

Racial Differences in Arterial Stiffness and Cognitive Function.R03MD011306 · NIMHD · SYRACUSE UNIVERSITY · PI HEFFERNAN, KEVIN SCOTT · 2017 to 2018
$150k
NIMHD NIH HHS R03 MD011306
6 · The paper itself

Abstract

Background: The interactions between large artery function and neurovascular coupling (NVC) are emerging as important contributors to cognitive health. Women are disproportionally affected by Alzheimer's disease and related dementia later in life. Understanding large artery correlates of NVC in young women may help with preservation of cognitive health with advancing age. Purpose: To explore the association between large artery function, NVC and cognitive performance in young women. Methods: Vascular measurements were made in 61 women (21 ± 4 yrs) at rest and during a cognitive challenge (Stroop task). Transcranial Doppler was used to measure left middle cerebral artery (MCA) maximum velocity (V Results: MCA V Conclusions: NVC was associated with cognitive function in young women. Carotid artery function assessed as carotid compliance and carotid reactivity may contribute to optimal NVC in young women through increased blood flow delivery and reduced blood flow pulsatility.

Indexed as

blood pressurecerebral pulsatilitycognitive functionneurovascular couplingvascular stiffness

Identifiers

PMID36035945
PMCPMC9411931
OpenAlexW4291155803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.