Evidence map›Paper›PMID 36035620›Full record

ArticleMedicine in microecology2022

Oral intake of Kluyveromyces marxianus B0399 plus Lactobacillus rhamnosus CECT 30579 to mitigate symptoms in COVID-19 patients: A randomized open label clinical trial.

Vicente Navarro-López, Adriana Hernández-Belmonte, Maria Isabel Pérez Soto, Maikel Ayo-González, Guillermo Losa-Rodríguez, Esther Ros-Sánchez, Maravillas Martínez-Gabarrón, Pedro Sánchez-Pellicer, Juan Aguera-Santos, Eva Núñez-Delegido and 3 more

Abstract read
In one paragraph

Article in Medicine in microecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. The role of acute rehabilitation in COVID-19 patients.European journal of physical and rehabilitation medicine · 2023
    Observational
  8. Novel yeasts with potential probiotic characteristics isolated from the endogenous ferment of artisanal Minas cheese.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Vicente Navarro-LópezMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de Los Jerónimos N 135, 30107, Murcia, Spain.
Adriana Hernández-BelmonteClinical Microbiology and Infectious Disease Unit, Hospital Universitario Del Vinalopó, 03293, Elche, Spain.
Maria Isabel Pérez SotoDepartment of Internal Medicine, Hospital Universitario Del Vinalopó, 03293, Elche, Spain.
Maikel Ayo-GonzálezDepartment of Hospital Homecare Unit, Hospital Universitario Del Vinalopó, 03293, Elche, Spain.
Guillermo Losa-RodríguezDepartment of Hospital Homecare Unit, Hospital Universitario Del Vinalopó, 03293, Elche, Spain.
Esther Ros-SánchezDepartment of Hospital Homecare Unit, Hospital Universitario Del Vinalopó, 03293, Elche, Spain.
Maravillas Martínez-GabarrónDepartment of Hospital Homecare Unit, Hospital Universitario Del Vinalopó, 03293, Elche, Spain.
Pedro Sánchez-PellicerMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de Los Jerónimos N 135, 30107, Murcia, Spain.
Juan Aguera-SantosMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de Los Jerónimos N 135, 30107, Murcia, Spain.
Eva Núñez-DelegidoMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de Los Jerónimos N 135, 30107, Murcia, Spain.
Beatriz Ruzafa-CostasMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de Los Jerónimos N 135, 30107, Murcia, Spain.
José Antonio Picó-MonllorDepartment of Pharmacology, Pediatrics and Organic Chemistry, Faculty of Pharmacy, Universidad Miguel Hernández de Elche, 03202, Elche, Spain.
Laura Navarro-MoratallaMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de Los Jerónimos N 135, 30107, Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the beginning of the SARS-CoV-2 pandemic, developing of new treatments to control the spread of infection and decrease morbidity and mortality are necessary. This prospective, open-label, case-control intervention study evaluates the impact of the oral intake of the probiotic yeast

Indexed as

ACE-2, angiotensin converting enzyme-2CECT, spanish type culture collectionCFU, colony-forming unitCOPD, chronic obstructive pulmonary diseaseCOVID-19COVID-19, coronavirus diseaseCURB-65, pneumoniae severity scoreDVT, deep vein thrombosisHHU, home hospitalization unitHT, HT:HypertensionIBS, Intestine Bowel SyndromeICU, intensive care unitMicrobiomeMicrobiotaPCR, polymerase chain reactionProbioticsRNA, ribonucleic adidSARS-CoV-2SD, standard deviationSPSS, Statistical Package for Social Science

Identifiers

PMID36035620
PMCPMC9398813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.