Evidence map›Paper›PMID 36035419›Full record

ArticleFrontiers in medicine2022

Multi-gene panel testing increases germline predisposing mutations' detection in a cohort of breast/ovarian cancer patients from Southern Italy.

Marcella Nunziato, Federica Di Maggio, Matilde Pensabene, Maria Valeria Esposito, Flavio Starnone, Carmine De Angelis, Alessandra Calabrese, Massimiliano D'Aiuto, Gerardo Botti, Sabino De Placido and 2 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Multigene panel testing reveals the spectrum of non-BRCA germline variants in BRCA1/2-negative breast, ovarian, and prostate cancer patients from a Turkish cohort.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  5. Genetic landscape of Romanian PPGLs.Journal of cellular and molecular medicine · 2024
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  9. A Novel DNA Variant inInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marcella NunziatoCEINGE-Biotecnologie Avanzate, Naples, Italy.
Federica Di MaggioCEINGE-Biotecnologie Avanzate, Naples, Italy.
Matilde PensabeneDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Maria Valeria EspositoCEINGE-Biotecnologie Avanzate, Naples, Italy.
Flavio StarnoneCEINGE-Biotecnologie Avanzate, Naples, Italy.
Carmine De AngelisDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Alessandra CalabreseDivision of Breast Surgery, Department of Breast Disease, National Cancer Institute, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) "Fondazione G. Pascale," Naples, Italy.
Massimiliano D'AiutoClinica Villa Fiorita, Aversa, Italy.
Gerardo BottiScientific Directorate, National Cancer Institute, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) "Fondazione G. Pascale," Naples, Italy.
Sabino De PlacidoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Valeria D'ArgenioCEINGE-Biotecnologie Avanzate, Naples, Italy.
Francesco SalvatoreCEINGE-Biotecnologie Avanzate, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common neoplasia in females worldwide, about 10% being hereditary/familial and due to DNA variants in cancer-predisposing genes, such as the highly penetrant

Indexed as

breast cancerDNA repairgenomic predisposition to diseasemultigene panelNGS sequencingovarian cancerpredictive medicine

Identifiers

PMID36035419
PMCPMC9403188

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.