Evidence map›Paper›PMID 36035382›Full record

ArticleFrontiers in medicine2022

Dry eye disease and tear film assessment through a novel non-invasive ocular surface analyzer: The OSA protocol.

María Carmen Sánchez-González, Raúl Capote-Puente, Marta-C García-Romera, Concepción De-Hita-Cantalejo, María-José Bautista-Llamas, Carmen Silva-Viguera, José-María Sánchez-González

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Repeatability and Reproducibility of the Dry Eye Analyzer in Participants With and Without Symptoms of Dry Eye.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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  2. Review
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  16. Tear film layers and meibomian gland assessment in patients with type 1 diabetes mellitus using a noninvasive ocular surface analyzer: a cross-sectional case-control study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
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  18. Evaluation of CelligentDiagnostics (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Carmen Sánchez-GonzálezVision Science Research Group, Vision Sciences of the University of Seville (CIVIUS), Department of Physics of Condensed Matter, Optics Area, University of Seville, Seville, Spain.
Raúl Capote-PuenteVision Science Research Group, Vision Sciences of the University of Seville (CIVIUS), Department of Physics of Condensed Matter, Optics Area, University of Seville, Seville, Spain.
Marta-C García-RomeraVision Science Research Group, Vision Sciences of the University of Seville (CIVIUS), Department of Physics of Condensed Matter, Optics Area, University of Seville, Seville, Spain.
Concepción De-Hita-CantalejoVision Science Research Group, Vision Sciences of the University of Seville (CIVIUS), Department of Physics of Condensed Matter, Optics Area, University of Seville, Seville, Spain.
María-José Bautista-LlamasVision Science Research Group, Vision Sciences of the University of Seville (CIVIUS), Department of Physics of Condensed Matter, Optics Area, University of Seville, Seville, Spain.
Carmen Silva-VigueraVision Science Research Group, Vision Sciences of the University of Seville (CIVIUS), Department of Physics of Condensed Matter, Optics Area, University of Seville, Seville, Spain.
José-María Sánchez-GonzálezVision Science Research Group, Vision Sciences of the University of Seville (CIVIUS), Department of Physics of Condensed Matter, Optics Area, University of Seville, Seville, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the role of OSA as a new instrument in the study of dry eye, and we recommend a protocol for conducting the tests as well as describe the advantages and disadvantages compared with other instruments. A comparison with other ocular surface devices (Tearscope Plus, Keratograph 5M, anterior-segment ocular coherence tomography, Easy Tear View-Plus, LipiView, IDRA, and LacryDiag) were presented due to manual or automatic procedure and objective or subjective measurements. The purpose of this study was to describe the OSA as new non-invasive dry eye disease diagnostic device. The OSA is a device that can provide accurate, non-invasive and easy-to-use parameters to specifically interpret distinct functions of the tear film. This OSA protocol proposed a lesser to higher non-invasive ocular surface dry eye disease tear film diagnostic methodology. A complete and exhaustive OSA and OSA Plus examination protocol was presented within the subjective questionnaire (Dry Eye Questionnaire 5, DEQ5), limbal and bulbar redness classification (within the Efron grade Scale, interferometry lipid layer thickness (LLT) (according to Guillon pattern), tear meniscus height (manually or automatic), first and mean non-invasive break up time (objective and automatic) and meibomian gland (MG) dysfunction grade and percentage (objective and automatic). The OSA and OSA Plus devices are novel and relevant dry eye disease diagnostic tools; however, the automatization and objectivity of the measurements can be increased in future software or device updates. The new non-invasive devices supposed represent a renewal in the dry eye disease diagnosis and introduce a tendency to replace the classic invasive techniques that supposed less reliability and reproducibility.

Indexed as

dry eye disease (DED)dry eye syndrome diagnosticnon-invasive ocular devicesocular surface analyzertear film

Identifiers

PMID36035382
PMCPMC9399399

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.