Evidence map›Paper›PMID 36035304›Full record

ArticleComputational and mathematical methods in medicine2022

A Ferroptosis-Related Gene Signature for Predicting Survival and Immunotherapy Effect in Renal Cancer.

Liang Tong, Zhao-Fa Yin, Liang Peng, Yu-Ting Li, Rong Liu, Jia-Rong Cai, Le Kang

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Liang TongDepartment of Urology, Loudi Central Hospital of Hunan Province, Loudi, China.
Zhao-Fa YinDepartment of Urology, Loudi Central Hospital of Hunan Province, Loudi, China.
Liang PengDepartment of Urology, Loudi Central Hospital of Hunan Province, Loudi, China.
Yu-Ting LiDepartment of Urology, Loudi Central Hospital of Hunan Province, Loudi, China.
Rong LiuDepartment of Urology, Loudi Central Hospital of Hunan Province, Loudi, China.
Jia-Rong CaiDepartment of Urology, Loudi Central Hospital of Hunan Province, Loudi, China.
Le KangDepartment of Urology, Loudi Central Hospital of Hunan Province, Loudi, China.ORCID https://orcid.org/0000-0002-2730-4229
Loudi Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Most recently, no efficient prognostic indictor is present for kidney cancer. Thus, we aimed to build and validate a new prognostic gene signature for renal cancer patients using the Cancer Genomic Atlas (TCGA). Methods: A "time-dependent receiver operating characteristic (tROC)" curve was generated, and a log-rank test was performed to assess the performance of the biomarker in training and validation. A "ferroptosis-related gene signature" was developed. In different training and validations sets, tROC and log-rank test were used to validate the biomarker's performance. Results: In the training set with a Conclusion: We developed and validated a "ferroptosis-related gene signature" that can be sued for patients with kidney cancer. It can also assist in facilitating the plan for treatment and risk stratification.

Indexed as

FerroptosisKidney NeoplasmsBiomarkers, TumorHumansImmunotherapyPrognosisBiomarkers, Tumor

Identifiers

PMID36035304
PMCPMC9402346
OpenAlexW4292343331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.