Evidence map›Paper›PMID 36035222›Full record

ArticleOxidative medicine and cellular longevity2022

Differential Effects of Dietary White Meat and Red Meat on NAFLD Progression by Modulating Gut Microbiota and Metabolites in Rats.

Juan Li, Yuting Li, Shufen Feng, Kaiyin He, Liliangzi Guo, Weiwei Chen, Min Wang, Lixian Zhong, Chutian Wu, Xiaojuan Peng and 1 more

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juan LiDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0003-0100-8656
Yuting LiDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0003-4407-8662
Shufen FengDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0001-5750-4830
Kaiyin HeDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0003-3884-9758
Liliangzi GuoDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0003-1521-6245
Weiwei ChenDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0003-2289-3578
Min WangDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0001-9746-7384
Lixian ZhongDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0001-6638-8667
Chutian WuDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0002-7217-1840
Xiaojuan PengDepartment of Endocrinology, Liuzhou People's Hospital, Liuzhou, Guangxi 545006, China.ORCID https://orcid.org/0000-0001-8140-2471
Shaohui TangDepartment of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510630, China.ORCID https://orcid.org/0000-0002-1859-0876

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the effects of dietary white meat (grass carp and chicken) and red meat (pork and beef) on metabolic parameters, including the intestinal microbiota and its metabolites (SCFAs and bile acids) in NAFLD rats induced by high-fat diet. Methods: NAFLD rats were randomly assigned to five groups: NAFLD group, grass carp group, chicken group, pork group, and beef group (10 rats in each group), and these rats were fed for 8 weeks using the high-fat diet, grass carp-based diet, chicken-based diet, pork-based diet, and beef-based diet, respectively. At the end of the intervention, NAFLD-related metabolic indexes, intestinal flora, and its metabolites were measured. Results: The grass carp-based diet significantly improved hepatic pathological changes and glycolipid metabolism, and the chicken-based diet only partially improved the metabolic parameters. However, NAFLD progression was observed in the pork group and the beef group. What is more, the white meat-based diet-mediated changes in the enrichment of beneficial bacteria (such as Conclusion: The dietary white meat and red meat modulating gut microbiota and its metabolites may favor and aggravate NAFLD in rats, respectively.

Indexed as

CarpsGastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseRed MeatAnimalsCattleChickensDiet, High-FatRats

Identifiers

PMID36035222
PMCPMC9410827

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.