ArticleAnnals of translational medicine2022
Novel application of 3D printed microporous prosthesis to repair humeral nonunion with segmental bone defects: a case report.
Article in Annals of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Humerus Non-union with Segmental Bone Loss Treated with 3D-printed Prosthesis: A Case Report.Journal of orthopaedic case reports · 2026Article
- Integration of locking screw fixation into 3D-printed patient-specific porous titanium implants enhances osseointegration: anJournal of veterinary science · 2025Article
- Emerging applications of 3D printed microporous prosthesis in nonunion repair: mechanisms and therapeutic potential.Annals of translational medicine · 2022Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Nonunion of the humeral shaft can turn into bone defects. There is no consensus on the optimal treatment of humeral shaft nonunion with bone defects. Herein, we presented a single case of a patient with a 9.5 cm humerus shaft bone defect treated with a 3D printed Ti Case Description: A 53-year-old female who injured her left upper limb by falling was diagnosed with a fracture of the left humeral shaft. The fracture was treated with open reduction and internal fixation. Nine months postoperatively, radiography examination indicated humeral nonunion with a 9.5 cm segmental bone defect. A 3D printing technology was then used to design and fabricate a customized microporous prosthesis with an intramedullary nail and lateral plates. A two-stage surgical strategy was performed, including radical debridement, temporary fixation for the induced membrane formation, and the implantation of the prosthesis. At 18 months of follow-up, encouraging clinical outcomes were observed. The prosthesis remained stable in the original implantation area and callus formation was found at the contact end of the prosthesis and bone stump. The upper limb functions returned to normal with a satisfactory functional score. Also, no complications were found. Conclusions: Reconstruction with a 3D printed microporous prosthesis might be used as an alternative for the repair of large segmental bone defects of limbs.
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