Evidence map›Paper›PMID 36034823›Full record

ArticleFrontiers in pharmacology2022

Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.

Jicang Wang, Ke Wang, Lulu Ding, Pengli Zhao, Cai Zhang, Hongwei Wang, Zijun Yang, Zongping Liu

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Application of Modulators of CaInternational journal of molecular sciences · 2025
    Article
  7. Antioxidants (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Frontiers in molecular biosciences · 2024
    Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jicang WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Ke WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Lulu DingCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Pengli ZhaoCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Cai ZhangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Hongwei WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Zijun YangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Zongping LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) is a toxic heavy metal extensively used in industrial and agricultural production. Among the main mechanisms of Cd-induced liver damage is oxidative stress. Quercetin (QE) is a natural antioxidant. Herein, the protective effect of QE on Cd-induced hepatocyte injury was investigated. BRL-3A cells were treated with 12.5 μmol/L CdCl

Indexed as

apoptosisBRL-3A cellscadmiumNrf2-Keap1 pathwayoxidative damagequercetin

Identifiers

PMID36034823
PMCPMC9403134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.