Evidence map›Paper›PMID 36034793›Full record

ReviewFrontiers in pharmacology2022

Taccalonolides: Structure, semi-synthesis, and biological activity.

Yan Li, Yu-Feng Du, Feng Gao, Jin-Bu Xu, Ling-Li Zheng, Gang Liu, Yu Lei

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Pharmacokinetic and Biodistribution Studies of [ACS medicinal chemistry letters · 2025
    Article
  4. Antitrypanosomal and Antileishmanial Activities ofMolecules (Basel, Switzerland) · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan LiDepartment of Pharmacy, The First Afflicted Hospital of Chengdu Medical College, Chengdu, China.
Yu-Feng DuSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
Feng GaoSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
Jin-Bu XuSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
Ling-Li ZhengDepartment of Pharmacy, The First Afflicted Hospital of Chengdu Medical College, Chengdu, China.
Gang LiuDepartment of Pharmacy, The First Afflicted Hospital of Chengdu Medical College, Chengdu, China.
Yu LeiDepartment of Pharmacy, The First Afflicted Hospital of Chengdu Medical College, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microtubules are the fundamental part of the cell cytoskeleton intimately involving in cell proliferation and are superb targets in clinical cancer therapy today. Microtubule stabilizers have become one of the effectively main agents in the last decades for the treatment of diverse cancers. Taccalonolides, the highly oxygenated pentacyclic steroids isolated from the genus of

Indexed as

antitumormicrotubule-stabilizerpharmacological mechanismstructural classificationtaccalonolides

Identifiers

PMID36034793
PMCPMC9407980

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.