Evidence map›Paper›PMID 36034719›Full record

ArticleJournal of men's health2022

Evidence-based circumcision policy for Australia.

Brian J Morris, Athos Katelaris, Norman J Blumenthal, Mohamed Hajoona, Adrian C Sheen, Leslie Schrieber, Eugenie R Lumbers, Alex D Wodak, Phillip Katelaris

Open access · goldAbstract read
In one paragraph

Article in Journal of men's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Brian J MorrisSchool of Medical Sciences, University of Sydney, Sydney, NSW 2006, Australia.
Athos KatelarisDepartment of Urology, St George Hospital, Sydney, NSW 2217, Australia.
Norman J BlumenthalDepartment of Obstetrics and Gynaecology, SAN Clinic, Wahroonga, NSW 2076, Australia.
Mohamed HajoonaVictoria Circumcision Clinic, The Regent Medical Group, Preston, VIC 3072, Australia.
Adrian C SheenMulgoa Medical Centre, Mulgoa, NSW 2745, Australia.
Leslie SchrieberDepartment of Medicine, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Eugenie R LumbersSchool of Biomedical Sciences and Pharmacy, University of Newcastle, Pregnancy and Reproduction Program, Hunter Medical Research Institute, New Lambton Heights; Priority Research Centre for Reproductive Sciences, University of Newcastle, Callaghan, NSW 2308, Australia.
Alex D WodakSt Vincent's Hospital, Australian Tobacco Harm Reduction Association and Australia21, Darlinghurst, NSW 2010, Australia.
Phillip KatelarisKatelaris Urology, North Shore Private Hospital, St Leonards, NSW 2065, Australia.
Royal North Shore Hospital · AUHunter Medical Research Institute · AUSt George Hospital · AUSt Vincent's Hospital · AUUniversity of Sydney · AU

Funding

Productive and Leisure Activities and Cognition in Later LifeP20GM125526 · NIGMS · KUAKINI MEDICAL CENTER · PI WILLCOX, BRADLEY JOHN · 2019 to 2023
$12.0M
NIGMS NIH HHS P20 GM125526
6 · The paper itself

Abstract

The aim was (1) to perform an up-to-date systematic review of the male circumcision (MC) literature and (2) to determine the number of adverse medical conditions prevented by early MC in Australia. Searches of PubMed using "circumcision" with 39 keywords and bibliography searches yielded 278 publications meeting our inclusion criteria. Early MC provides immediate and lifetime benefits, including protection against: urinary tract infections, phimosis, inflammatory skin conditions, inferior penile hygiene, candidiasis, various STIs, and penile and prostate cancer. In female partners MC reduces risk of STIs and cervical cancer. A risk-benefit analysis found benefits exceeded procedural risks, which are predominantly minor, by approximately 200 to 1. It was estimated that more than 1 in 2 uncircumcised males will experience an adverse foreskin-related medical condition over their lifetime. An increase in early MC in Australia to mid-1950s prevalence of 85% from the current level of 18.75% would avoid 77,000 cases of infections and other adverse medical conditions over the lifetime for each annual birth cohort. Survey data, physiological measurements, and the anatomical location of penile sensory receptors responsible for sexual sensation indicate that MC has no detrimental effect on sexual function, sensitivity or pleasure. US studies found that early infant MC is cost saving. Evidence-based reviews by the AAP and CDC support early MC as a desirable public health measure. Although MC can be performed at any age, early MC maximizes benefits and minimises procedural risks. Parents should routinely be provided with accurate, up-to-date evidence-based information in an unbiased manner early in a pregnancy so that they have time to weigh benefits and risks of early MC and make an informed decision should they have a son. Parental choice should be respected. A well-trained competent practitioner is essential and local anaesthesia should be routinely used. Third party coverage of costs is advocated.

Indexed as

circumcision malecomplicationscost benefitinflammatory conditionspenile cancerpolicyprostate cancerrisk benefitsexual functionsexually transmitted infectionsurinary tract infection

Identifiers

PMID36034719
PMCPMC9409339
OpenAlexW4281909433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.