ReviewApplied biosafety : journal of the American Biological Safety Association2019
The Culture of Biosafety, Biosecurity, and Responsible Conduct in the Life Sciences: A Comprehensive Literature Review.
Review in Applied biosafety : journal of the American Biological Safety Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Review
- Rethinking governance of synthetic cells.Frontiers in bioengineering and biotechnology · 2026Article
- China's biosafety/biosecurity governance: evolution, challenges, and architecture design.Frontiers of medicine · 2025Article
- Unmet Expectations: Life Scientists' Views on Biorisk and Responsibility.Applied biosafety : journal of the American Biological Safety Association · 2025Article
- Discovering topics and trends in biosecurity law research: A machine learning approach.One health (Amsterdam, Netherlands) · 2025Article
- Article
- Ethical decision-making and role conflict in managing a scientific laboratory.Accountability in research · 2024Article
- Biosafety, biosecurity, and bioethics.Monash bioethics review · 2024Review
- Biological Containment for African Swine Fever (ASF) Laboratories and Animal Facilities: The Italian Challenge in Bridging the Present Regulatory Gap and Enhancing Biosafety and Biosecurity Measures.Animals : an open access journal from MDPI · 2024Article
- The whack-a-mole governance challenge for AI-enabled synthetic biology: literature review and emerging frameworks.Frontiers in bioengineering and biotechnology · 2024Review
- The Need for Biosecurity Education in Biotechnology Curricula.Biodesign research · 2023Article
- Bottlenecks and opportunities for synthetic biology biosafety standards.Nature communications · 2022Article
- Complementarity of International Instruments in the Field of Biosecurity.Frontiers in public health · 2022Review
- Management System Approach for Addressing Biosafety and Biosecurity of Emerging Pathogens in a Biosafety Level-3 Core Facility.Applied biosafety : journal of the American Biological Safety Association · 2021Article
- Building and implementing a multi-level system of ethical code for biologists under the Biological and Toxin Weapons Convention (BTWC) of the United Nations.Journal of biosafety and biosecurity · 2021Review
- Article
- South-to-south mentoring as a vehicle for implementing sustainable health security in Africa.One health outlook · 2021Article
- Exploring Goal Conflicts and How They Are Managed in a Biomedical Laboratory Using Rasmussen's Model of Boundaries.Applied biosafety : journal of the American Biological Safety Association · 2021Article
- The Culture of Biosafety, Biosecurity, and Responsible Conduct in the Life Sciences: A Comprehensive Literature Review.Applied biosafety : journal of the American Biological Safety Association · 2019Review
- Promoting Scientific Transparency to Facilitate the Safe and Open International Exchange of Biological Materials and Electronic Data.Tropical medicine and infectious disease · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Managing biological risks requires an organizational culture that holistically ensures the biosafety, biosecurity, and biocontainment of infectious disease agents and toxins, in addition to conducting science in a responsible manner, complying with relevant laws, regulations, guidelines, and policies, as well as emphasizing norms, values, and beliefs of the entire life sciences profession. Methods: Drawing upon the Federal Experts Security Advisory Panel's (FESAP's) 2014 recommendation to "strengthen a culture that emphasizes biosafety, laboratory biosecurity, and responsible conduct in the life sciences," we undertook a comprehensive literature review of the culture of biosafety, biosecurity, and responsible conduct in the life sciences, including metrics by which to evaluate interventions at the organizational level. Results: We identified 4031 unique citations published from January 2001 to January 2017 by searching the MEDLINE/PubMed, Scopus, Web of Science, and Global Health databases. In addition, a subset of 326 articles was reviewed in full. Discussion: We found that while there were discussions in the literature about specific elements of culture (management systems, leadership and/or personnel behavior, beliefs and attitudes, or principles for guiding decisions and behaviors), there was a general lack of integration of these concepts, as well as limited information about specific indicators or metrics and the effectiveness of training or similar interventions. Conclusion: We concluded that life scientists seeking to foster a culture of biosafety and biosecurity should learn from the substantial literature in analogous areas such as nuclear safety and security culture, high-reliability organizations, and the responsible conduct of research, among others.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.