Evidence map›Paper›PMID 36034507›Full record

ArticleJournal of neurosurgery. Case lessons2021

Spinal intramedullary hemangioblastoma and schwannoma collision tumor: illustrative case.

Matthew T Neal, Alexandra E Richards, Kara L Curley, Kliment Donev, Mark K Lyons, Maziyar A Kalani

Abstract readCase Reports
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew T NealDepartment of Neurosurgery, Mayo Clinic Arizona, Phoenix, Arizona; and.
Alexandra E RichardsDepartment of Neurosurgery, Mayo Clinic Arizona, Phoenix, Arizona; and.
Kara L CurleyDepartment of Neurosurgery, Mayo Clinic Arizona, Phoenix, Arizona; and.
Kliment DonevDepartment of Pathology, Mayo Clinic Minnesota, Rochester, Minnesota.
Mark K LyonsDepartment of Neurosurgery, Mayo Clinic Arizona, Phoenix, Arizona; and.
Maziyar A KalaniDepartment of Neurosurgery, Mayo Clinic Arizona, Phoenix, Arizona; and.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntramedullary spinal cord tumors represent a minority of intradural tumors. Among intramedullary spinal cord tumors, hemangioblastomas are uncommon, and schwannomas are extremely rare. Collision tumors are histologically distinct tumors that are intermingled and growing together. OBSERVATIONS: In this report, the authors describe a patient with a cervical intramedullary collision tumor involving a hemangioblastoma and schwannoma. To the authors' knowledge, no prior spinal intramedullary collision tumor involving multiple neoplasms has been described. The patient's presentation and management are described. LESSONS: Clinicians should consider the possibility of collision tumors when evaluating intramedullary spinal cord tumors, especially when patient presentation and radiographic findings are atypical. When tumors with similar radiographic characteristics form collision tumors, distinction using preoperative imaging can be extremely challenging. In addition, surgical management of intramedullary collision tumors, like that for all intramedullary spinal cord tumors, should involve meticulous perioperative care and a methodical surgical technique. Maximal safe resection will depend upon histopathological diagnosis, anatomical location of the tumor, presence of distinct dissection planes, and stability of neuromonitoring. Finally, ongoing research on the genetics of intramedullary spinal cord tumors may identify underlying genetic links for intramedullary hemangioblastomas and schwannomas.

Indexed as

collision tumorGTR = gross-total resectionHBL = hemangioblastomahemangioblastomaHIF1α = hypoxia-inducible factor 1αIMSCT = intramedullary spinal cord tumorIMS = intramedullary schwannomaintramedullary spinal cord tumorMRI = magnetic resonance imagingNF2 = neurofibromin 2schwannomaspineSTIR = short tau inversion recoveryT1WI = T1-weighted imagingT2WI = T2-weighted imagingVHL = von Hippel-Lindau

Identifiers

PMID36034507
PMCPMC9394162

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.