ArticleCurrent opinion in behavioral sciences2020
Variable specificity of memory trace reactivation during hippocampal sharp wave ripples.
Article in Current opinion in behavioral sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- A Brain-wide Neuronal Spiking and Behavioral Dataset for Working Memory-specific Activation and Reactivation in Mice.Neuroscience bulletin · 2026Article
- Human hippocampal ripples tune cortical responses based on predicted uncertainty.Nature neuroscience · 2026Article
- Hierarchical Replay of Multi-regional Sequential Spiking Associated with Working Memory.Neuroscience bulletin · 2025Article
- Engram mechanisms of memory linking and identity.Nature reviews. Neuroscience · 2024Review
- Coupling of Sharp Wave Events between Zebrafish Hippocampal and Amygdala Homologs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Backbone spiking sequence as a basis for preplay, replay, and default states in human cortex.Nature communications · 2023Article
- From single-neuron dynamics to higher-order circuit motifs in control and pathological brain networks.The Journal of physiology · 2023Article
- Cognition from the Body-Brain Partnership: Exaptation of Memory.Annual review of neuroscience · 2023Review
- Cognitive neuroscience perspective on memory: overview and summary.Frontiers in human neuroscience · 2023Article
- Sleep prevents catastrophic forgetting in spiking neural networks by forming a joint synaptic weight representation.PLoS computational biology · 2022Article
- Multiple-Timescale Representations of Space: Linking Memory to Navigation.Annual review of neuroscience · 2022Review
- Brain-wide interactions during hippocampal sharp wave ripples.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The shallow cognitive map hypothesis: A hippocampal framework for thought disorder in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2022Review
- Article
- Aperiodic sleep networks promote memory consolidation.Trends in cognitive sciences · 2021Review
- Endogenous memory reactivation during sleep in humans is clocked by slow oscillation-spindle complexes.Nature communications · 2021Article
- Article
- The evolving view of replay and its functions in wake and sleep.Sleep advances : a journal of the Sleep Research Society · 2020Review
- Naïve to expert: Considering the role of previous knowledge in memory.Brain and neuroscience advancesReview
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Hippocampal sharp wave-ripples (SWR) are thought to mediate brain-wide reactivation of memory traces in service of memory consolidation. However, rather than the faithful replay of neural activity observed during a specific experience, reactivation in both the hippocampus and downstream regions is more variable. We suggest that variable reactivation is a unifying feature of recurrent brain circuits. In the hippocampus, self-organized activation during offline states is constrained by existing attractor manifolds, or maps, and may be biased toward particular mapped locations by salient experience, which results in the appearance of experience-specific replay. Similarly, the impact of SWR-associated reactivation on downstream regions is not a simple transfer of hippocampal representational content. Rather, the response of downstream regions depends on a transformation function, defined by both the feedforward and local circuit architecture, as well as the 'listening state' of the downstream region. We hypothesize that SWRs act as a multiplexed signal, the mnemonic specificity of which is largely determined by this transformation function, and discuss the implications of this framing for theories of systems consolidation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.