ArticleiScience2022
Randomized controlled trial for time-restricted eating in overweight and obese young adults.
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05730231 (Comparison of Calorie Restriction With Early Time-restricted Eating and Calorie Restriction With Mid-day Time-restricted Eating and Daily Calorie Restriction), which is not on this map. Cited by 50 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Calorie Restriction With Early Time-restricted Eating and Calorie Restriction With Mid-day Time-restricted Eating and Daily Calorie Restriction
Who cites it
50 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Pooled it
- Time-restricted eating in overweight and obese adults: an evidence summary and clinical recommendations.Journal of health, population, and nutrition · 2026Pooled it
- Early, midday, and late time-restricted eating impact on anthropometry and cardiometabolic health: a network meta-analysis of RCTs.Frontiers in nutrition · 2026Pooled it
- The Effects of Intermittent Fasting on Inflammatory Markers in Adults: A Systematic Review and Pairwise and Network Meta-Analyses.Nutrients · 2025Pooled it
- Effectiveness and safety of intermittent fasting on blood pressure in adults with overweight or obesity: a systematic review.International journal of obesity (2005) · 2025Pooled it
- The effectiveness of fasting regimens on serum levels of some major weight regulating hormones: a GRADE-assessed systematic review and meta-analysis in randomized controlled trial.Journal of health, population, and nutrition · 2025Pooled it
- Effects of time-restricted eating on body composition and metabolic parameters in overweight and obese women: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Pooled it
- Comparing caloric restriction regimens for effective weight management in adults: a systematic review and network meta-analysis.The international journal of behavioral nutrition and physical activity · 2024Pooled it
- Circadian alignment of food intake and glycaemic control by time-restricted eating: A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2024Pooled it
- The effects of time-restricted eating on sleep in adults: a systematic review of randomized controlled trials.Frontiers in nutrition · 2024Pooled it
- Time-restricted eating versus dietetic guidance on glycaemic outcomes in adults at risk of type 2 diabetes: a non-inferiority randomised clinical trial.Diabetologia · 2026Trial
- Do the Effects of Early Time-Restricted Eating Vary by Cardiometabolic Phenotype, Age, Sex, or Race? A Secondary Analysis of a Randomized Controlled Trial.The Journal of nutrition · 2026Trial
- Impact of Intended Isocaloric Early versus Late Time-Restricted Eating on Plasma Lipidome in Women with Overweight or Obesity: Secondary Analysis of the ChronoFast Trial.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Trial
- A Qualitative Exploration of Facilitators and Barriers to Early Time-Restricted Eating: Insights From a Randomised Controlled Trial.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Trial
- Flexible time-restricted eating combined with exercise in a free-living setting for middle-aged women with overweight/obesity: a randomized controlled trial.Nature communications · 2025Trial
- Effect of a ketogenic diet, time-restricted eating, or alternate-day fasting on weight loss in adults with obesity: a randomized clinical trial.BMC medicine · 2025Trial
- Time-Restricted Eating and Sleep, Mood, and Quality of Life in Adults With Overweight or Obesity: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2025Trial
- Effects of early, late and self-selected time-restricted eating on visceral adipose tissue and cardiometabolic health in participants with overweight or obesity: a randomized controlled trial.Nature medicine · 2025Trial
- A Remote Time-Restricted Eating and Mindfulness Intervention Addressing Risk Factors Associated with Early-Onset Colorectal Cancer Demonstrates Feasibility and Acceptability among Young Adults: A Randomized Controlled Pilot Trial.Nutrition and cancer · 2025Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Time-restricted eating (TRE) is known to improve metabolic health, whereas very few studies have compared the effects of early and late TRE (eTRE and lTRE) on metabolic health. Overweight and obese young adults were randomized to 6-h eTRE (eating from 7 a.m. to 1 p.m.) (n = 21), 6-h lTRE (eating from 12 p.m. to 6 p.m.) (n = 20), or a control group (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.