Evidence map›Paper›PMID 36034090›Full record

ArticleStatistical science : a review journal of the Institute of Mathematical Statistics2022

Statistical Challenges in Tracking the Evolution of SARS-CoV-2.

Lorenzo Cappello, Jaehee Kim, Sifan Liu, Julia A Palacios

Abstract read
In one paragraph

Article in Statistical science : a review journal of the Institute of Mathematical Statistics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Efficient Bayesian Phylogenetics under the Infinite Sites Model.bioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Article
  4. An efficient coalescent model for heterochronously sampled molecular data.Journal of the American Statistical Association · 2024
    Article
  5. Article
  6. Article
  7. Statistical Challenges in Tracking the Evolution of SARS-CoV-2.Statistical science : a review journal of the Institute of Mathematical Statistics · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lorenzo CappelloDepartments of Economics and Business, Universitat Pompeu Fabra, 08005, Spain.
Jaehee KimDepartment of Computational Biology, Cornell University, Ithaca, New York 14853, USA\.
Sifan LiuDepartment of Statistics, Stanford University, Stanford, California 94305, USA.
Julia A PalaciosDepartments of Statistics and Biomedical Data Sciences, Stanford University, Stanford, California 94305, USA.

Funding

Scalable Coalescent Inference for Large Data SetsR01GM131404 · NIGMS · STANFORD UNIVERSITY · PI PALACIOS, JULIA · 2018 to 2021
$1.2M
NIGMS NIH HHS R01 GM131404
6 · The paper itself

Abstract

Genomic surveillance of SARS-CoV-2 has been instrumental in tracking the spread and evolution of the virus during the pandemic. The availability of SARS-CoV-2 molecular sequences isolated from infected individuals, coupled with phylodynamic methods, have provided insights into the origin of the virus, its evolutionary rate, the timing of introductions, the patterns of transmission, and the rise of novel variants that have spread through populations. Despite enormous global efforts of governments, laboratories, and researchers to collect and sequence molecular data, many challenges remain in analyzing and interpreting the data collected. Here, we describe the models and methods currently used to monitor the spread of SARS-CoV-2, discuss long-standing and new statistical challenges, and propose a method for tracking the rise of novel variants during the epidemic.

Indexed as

Bayesian nonparametricsbirth-death processescoalescentgenetic epidemiologyPhylodynamicsSIR models

Identifiers

PMID36034090
PMCPMC9409356

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.