Evidence map›Paper›PMID 36033830›Full record

ArticleDisease markers2022

Effect of Bicalutamide Combined with Docetaxel on Serum PSA and VEGF Levels in Patients with Advanced Prostate Carcinoma.

Zhaoxin Guo, Xiaolin Hu, Renguang Lv, Yongzhen Zhang, Liwei Meng, Zhaoxu Liu, Lei Yan

Abstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhaoxin GuoDepartment of Urology, Qilu Hospital of Shandong University, Jinan, 250012 Shandong, China.
Xiaolin HuDepartment of Endocrinology, Jinan Central Hospital, Jinan, 250033 Shandong, China.
Renguang LvDepartment of Urology, Jinan Seventh People's Hospital, Jinan, 251400 Shandong, China.
Yongzhen ZhangDepartment of Urology, Qilu Hospital of Shandong University, Jinan, 250012 Shandong, China.
Liwei MengDepartment of Urology, Qilu Hospital of Shandong University, Jinan, 250012 Shandong, China.
Zhaoxu LiuDepartment of Urology, Qilu Hospital of Shandong University, Jinan, 250012 Shandong, China.
Lei YanDepartment of Urology, Qilu Hospital of Shandong University, Jinan, 250012 Shandong, China.ORCID https://orcid.org/0000-0001-8996-3839

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effect of bicalutamide combined with docetaxel on the levels of prostate-specific antigen (PSA) in serum and vascular endothelial growth factor (VEGF) in patients with advanced prostate carcinoma (PCa). Methods: The clinical data of 103 patients with advanced PCa at our hospital between Feb. 2020 and Feb. 2021 were retrospectively analyzed, the 90 of whom screened by inclusion and exclusion criteria were finally chosen as research objects. They were divided into a control group and an experimental group according to the order of admission, with 45 cases in each group. The control group was treated with conventional treatment, while the experimental group underwent the combination of bicalutamide and docetaxel, and the clinical indices of the two groups were compared. Results: After treatment, the serum indices in the experimental group were remarkably lower than those in the control group ( Conclusion: The implementation of bicalutamide combined with docetaxel in patients with advanced PCa is effective in reducing the inflammatory expression and improving quality of life and has a higher safety profile. Compared with conventional treatment, this method is of high application value, and further studies will help establish a better solution for such patients.

Indexed as

CarcinomaProstatic NeoplasmsAnilidesDocetaxelHumansMaleNitrilesProstateProstate-Specific AntigenQuality of LifeRetrospective StudiesTosyl CompoundsVascular Endothelial Growth Factor AAnilidesbicalutamideDocetaxelNitrilesProstate-Specific AntigenTosyl CompoundsVascular Endothelial Growth Factor A

Identifiers

PMID36033830
PMCPMC9402358

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.